Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 14/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9146933 | 0.81 | LTA4H (0.44) | APPCYP1A2 | |
| SCHEMBL9323735 | 0.81 | MAPT (0.41) | APP | |
| SCHEMBL28456471 | 0.81 | MEN1 (0.39) | APP | |
| SCHEMBL4821478 | 0.78 | MAOA (0.33) | — | |
| SCHEMBL4991354 | 0.77 | ALDH1A3 (0.49) | — | |
| SCHEMBL15514159 | 0.77 | CHRNA7 (0.44) | CYP2D6PMP22 | |
| SCHEMBL9267292 | 0.76 | L3MBTL1 (0.54) | — | |
| SCHEMBL1657430 | 0.76 | APP (0.53) | APP | |
| SCHEMBL4996149 | 0.75 | PKM (0.39) | — | |
| SCHEMBL11867619 | 0.75 | APP (0.61) | APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7611909-B1 | Acridinium compound for use in the concurrent detection of target analytes in immunoassays or nucleic acid assays | SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) | 2009-11-03 | — | — | US | disclosed |
| EP-1104405-B1 | NEAR INFRARED CHEMILUMINESCENT ACRIDINIUM COMPOUNDS AND USES THEREOF | SIEMENS HEALTHCARE DIAGNOSTICS (US) | 2009-02-18 | — | — | EP | disclosed |
| US-7459284-B2 | Chemiluminescent acridinium compounds and analogues thereof as substrates of hydrolytic enzymes | SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) | 2008-12-02 | — | — | US | disclosed |
| US-20060202179-A1 | Chemiluminescent Acridinium Compounds and Analogues thereof as Substrates of Hydrolytic Enzymes | BAYER CORPORATION (US) | 2006-09-14 | — | — | US | disclosed |
| US-7097995-B2 | Chemiluminescent acridinium compounds and analogues thereof as substrates of hydrolytic enzymes | BAYER CORP. (US) | 2006-08-29 | — | — | US | disclosed |
| US-7083986-B2 | Near infrared chemiluminescent acridinium compounds and uses thereof | BAYER HEALTHCARE LLC (US) | 2006-08-01 | — | — | US | disclosed |
| EP-1203091-B1 | CHEMILUMINESCENT SUBSTRATES OF HYDROLYTIC ENZYMES SUCH AS PHOSPHATASES | BAYER AG (US) | 2005-03-16 | — | — | EP | disclosed |
| US-20050032147-A1 | Chemiluminescent acridinum compounds and analogues thereof as substrates of hydrolytic enzymes | BAYER CORPORATION | 2005-02-10 | — | — | US | disclosed |
| US-6783948-B1 | USED IN DIAGNOSTIC IMMUNOASSAYS; HAS DISTINCTLY DIFFERENT LIGHT EMISSION CHARACTERISTICS (EMISSION WAVELENGTH, KINETICS, OR QUANTUM YIELD) | BAYER CORPORATION | 2004-08-31 | — | — | US | disclosed |
| US-20020076823-A1 | Near infrared chemiluminescent acridinium compounds and uses thereof | BAYER CORPORATION (US) | 2002-06-20 | — | — | US | disclosed |
| EP-1203091-A1 | CHEMILUMINESCENT SUBSTRATES OF HYDROLYTIC ENZYMES SUCH AS PHOSPHATASES | Bayer Corporation (US) | 2002-05-08 | — | — | EP | disclosed |
| US-6355803-B1 | COMPOUND COMPRISING EXTENDED, COPLANAR, CONJUGATED SYSTEM, FORMED BY ATTACHMENT OF FUNCTIONAL GROUP COMPRISING AROMATIC RING AND ELECTRON-DONATING GROUP ON ACRIDINIUM NUCLEUS, WHICH MAINTAINS COPLANARITY DURING LIGHT EMISSION | BAYER CORPORATION | 2002-03-12 | — | — | US | disclosed |
| EP-1104405-A1 | NEAR INFRARED CHEMILUMINESCENT ACRIDINIUM COMPOUNDS AND USES THEREOF | Bayer Corporation (US) | 2001-06-06 | — | — | EP | disclosed |
| WO-2001009372-A1 | CHEMILUMINESCENT SUBSTRATES OF HYDROLYTIC ENZYMES SUCH AS PHOSPHATASES | BAYER CORPORATION (US) | 2001-02-08 | — | — | WO | disclosed |
| WO-2000009487-A9 | NEAR INFRARED CHEMILUMINESCENT ACRIDINIUM COMPOUNDS AND USES THEREOF | BAYER AG (US) | 2000-06-22 | — | — | WO | disclosed |
| WO-2000009487-A1 | NEAR INFRARED CHEMILUMINESCENT ACRIDINIUM COMPOUNDS AND USES THEREOF | BAYER CORPORATION (US) | 2000-02-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050032147-A1 | Chemiluminescent acridinum compounds and analogues thereof as substrates of hydrolytic enzymes | MPO, LPO, PGLS | APP 1894/4885CYP1A2 252/4885CYP2D6 225/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.