Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | RAB9A | P51151 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.30 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.30 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.30 |
| ▸ | DRD1 | P21728 | 1/20 | 0.30 |
| ▸ | DRD4 | P21917 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4202435 | 0.90 | RAB9A (0.32) | ALDH1A1RAB9AMEN1MAPTKMT2A | |
| SCHEMBL5613965 | 0.84 | ATP4A (0.35) | ALDH1A1RAB9AMEN1MAPTKMT2A | |
| SCHEMBL5613855 | 0.84 | ALDH1A1 (0.37) | ALDH1A1RAB9AKDM4ESMN1; SMN2LMNA | |
| SCHEMBL5613884 | 0.83 | HTR1A (0.35) | ALDH1A1RAB9AMEN1MAPTKMT2A | |
| SCHEMBL5613944 | 0.82 | MAPK8 (0.38) | ALDH1A1RAB9AMEN1KMT2AKDM4E | |
| SCHEMBL4193399 | 0.82 | CYP1A2 (0.34) | ALDH1A1RAB9AMEN1MAPTKMT2A | |
| SCHEMBL4197137 | 0.82 | MEN1 (0.41) | ALDH1A1RAB9AMEN1MAPTKMT2A | |
| SCHEMBL4190547 | 0.81 | MAPK9 (0.39) | ALDH1A1RAB9AMEN1MAPTKMT2A | |
| SCHEMBL7707025 | 0.81 | NAAA (0.32) | RAB9AMEN1MAPTKMT2ALMNA | |
| SCHEMBL4203404 | 0.81 | PTGS1 (0.36) | ALDH1A1RAB9AMEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2026802-A2 | JNK INHIBITORS FOR TREATMENT OF SKIN DISEASES | Laboratoires Serono SA (CH) | 2009-02-25 | — | — | EP | disclosed |
| WO-2007141224-A2 | JNK INHIBITORS FOR TREATMENT OF SKIN DISEASES | LABORATOIRES SERONO SA (CH) | 2007-12-13 | — | — | WO | disclosed |