Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SYK | P43405 | 1/20 | 0.30 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.30 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4192500 | 0.85 | NAAA (0.42) | NAAARAB9ALMNAMAPT | |
| SCHEMBL7707443 | 0.81 | RAB9A (0.44) | RAB9AMEN1LMNAMAPTKMT2A | |
| SCHEMBL4194795 | 0.81 | ALDH1A1 (0.32) | RAB9AMEN1LMNAMAPTKMT2A | |
| SCHEMBL7707461 | 0.79 | CYP11B1 (0.36) | RAB9AMEN1LMNAMAPTKMT2A | |
| SCHEMBL4202435 | 0.79 | RAB9A (0.32) | RAB9AMEN1LMNAMAPTKMT2A | |
| SCHEMBL4203404 | 0.79 | PTGS1 (0.36) | RAB9AMEN1LMNAMAPTKMT2A | |
| SCHEMBL4203402 | 0.78 | RAB9A (0.43) | RAB9AMEN1LMNAMAPTKMT2A | |
| SCHEMBL4197270 | 0.77 | PTGS1 (0.36) | RAB9AMEN1MAPTKMT2A | |
| SCHEMBL4192595 | 0.77 | MAPK9 (0.36) | RAB9AMEN1LMNAKMT2A | |
| SCHEMBL7710188 | 0.76 | LMNA (0.40) | RAB9AMEN1LMNAMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1240164-A1 | BENZAZOLE DERIVATIVES AND THEIR USE AS JNK MODULATORS | Applied Research Systems ARS Holding N.V. (AN) | 2002-09-18 | — | — | EP | claimed |
| WO-2001047920-A1 | BENZAZOLE DERIVATIVES AND THEIR USE AS JNK MODULATORS | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2001-07-05 | — | — | WO | claimed |