Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | PGK1 | P00558 | 1/20 | 0.34 |
| ▸ | PGK2 | P07205 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.33 |
| ▸ | CXCR4 | P61073 | 2/20 | 0.32 |
| ▸ | NOS1 | P29475 | 1/20 | 0.32 |
| ▸ | NOS2 | P35228 | 1/20 | 0.32 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.32 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.32 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.32 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5068245 | 0.98 | KCNH2 (0.36) | KCNH2POLBNPSR1PGK1PGK2 | |
| SCHEMBL4211475 | 0.98 | KCNH2 (0.36) | KCNH2POLBNPSR1PGK1PGK2 | |
| SCHEMBL8304696 | 0.77 | ALDH1A1 (0.50) | ALDH1A1LMNAMAPTCYP1A2CYP2D6 | |
| SCHEMBL18157891 | 0.73 | KCNH2 (0.41) | KCNH2POLBNPSR1PGK1PGK2 | |
| SCHEMBL4199571 | 0.71 | KCNH2 (0.40) | KCNH2POLBNPSR1PGK1PGK2 | |
| SCHEMBL4205985 | 0.71 | KCNH2 (0.40) | KCNH2POLBNPSR1PGK1PGK2 | |
| SCHEMBL23518523 | 0.70 | CYP1A2 (0.45) | ALDH1A1LMNAMAPTNOS1NOS2 | |
| SCHEMBL2161730 | 0.70 | POLB (0.45) | KCNH2POLBNPSR1PGK1PGK2 | |
| SCHEMBL18973873 | 0.70 | POLB (0.41) | KCNH2POLBNPSR1PGK1PGK2 | |
| SCHEMBL2476938 | 0.69 | KCNH2 (0.41) | KCNH2NPSR1PGK1PGK2HRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2892879-B1 | CATALYSTS BASED ON AMINO-SULFIDE LIGANDS FOR HYDROGENATION AND DEHYDROGENATION PROCESSES | GOUSSEV DMITRI (CA) | 2020-07-22 | — | — | EP | disclosed |
| US-9545624-B2 | Nickel containing hydrosilylation catalysts and compositions containing the catalysts | DOW CORNING CORPORATION (US) | 2017-01-17 | — | — | US | disclosed |
| US-9545624-B2 | Nickel containing hydrosilylation catalysts and compositions containing the catalysts | DOW CORNING CORPORATION (US) | 2017-01-17 | — | — | US | disclosed |
| US-9480977-B2 | Ruthenium containing hydrosilylation catalysts and compositions containing the catalysts | DOW CORNING CORPORATION (US) | 2016-11-01 | — | — | US | disclosed |
| US-9480977-B2 | Ruthenium containing hydrosilylation catalysts and compositions containing the catalysts | DOW CORNING CORPORATION (US) | 2016-11-01 | — | — | US | disclosed |
| US-9221041-B2 | Iridium containing hydrosilylation catalysts and compositions containing the catalysts | DOW CORNING CORPORATION (US) | 2015-12-29 | — | — | US | disclosed |
| US-9221041-B2 | Iridium containing hydrosilylation catalysts and compositions containing the catalysts | DOW CORNING CORPORATION (US) | 2015-12-29 | — | — | US | disclosed |
| US-20140275329-A1 | Ruthenium Containing Hydrosilylation Catalysts And Compositions Containing The Catalysts | DOW SILICONES CORPORATION | 2014-09-18 | — | — | US | disclosed |
| US-20140275329-A1 | Ruthenium Containing Hydrosilylation Catalysts And Compositions Containing The Catalysts | DOW SILICONES CORPORATION | 2014-09-18 | — | — | US | disclosed |
| US-20140231702-A1 | Cobalt Containing Hydrosilylation Catalysts and Compositions Containing the Catalysts | DOW CORNING CORPORATION | 2014-08-21 | — | — | US | disclosed |
| US-20140200349-A1 | Manganese Containing Hydrosilylation Catalysts and Compositions Containing the Catalysts | DOW CORNING CORPORATION (US) | 2014-07-17 | — | — | US | disclosed |
| US-20140182483-A1 | Titanium Containing Hydrosilylation Catalysts And Compositions Containing The Catalysts | DOW CORNING CORPORATION | 2014-07-03 | — | — | US | disclosed |
| US-20140182483-A1 | Titanium Containing Hydrosilylation Catalysts And Compositions Containing The Catalysts | DOW CORNING CORPORATION | 2014-07-03 | — | — | US | disclosed |
| US-20140183398-A1 | Nickel Containing Hydrosilylation Catalysts and Compositions Containing the Catalysts | DOW SILICONES CORPORATION | 2014-07-03 | — | — | US | disclosed |
| US-20140183398-A1 | Nickel Containing Hydrosilylation Catalysts and Compositions Containing the Catalysts | DOW SILICONES CORPORATION | 2014-07-03 | — | — | US | disclosed |
| WO-2013043874-A2 | MANGANESE CONTAINING HYDROSILYLATION CATALYSTS AND COMPOSITIONS CONTAINING THE CATALYSTS | DOW CORNING CORPORATION (US) | 2013-03-28 | — | — | WO | disclosed |
| WO-2013043785-A2 | NICKEL CONTAINING HYDROSILYLATION CATALYSTS AND COMPOSITIONS CONTAINING THE CATALYSTS | DOW CORNING CORPORATION (US) | 2013-03-28 | — | — | WO | disclosed |
| WO-2013043787-A2 | RUTHENIUM CONTAINING HYDROSILYLATION CATALYSTS AND COMPOSITIONS CONTAINING THE CATALYSTS | DOW CORNING CORPORATION (US) | 2013-03-28 | — | — | WO | disclosed |
| WO-2013043783-A2 | COBALT CONTAINING HYDROSILYLATION CATALYSTS AND COMPOSITIONS CONTAINING THE CATALYSTS | DOW CORNING CORPORATION (US) | 2013-03-28 | — | — | WO | disclosed |
| US-20090216044-A1 | METHOD FOR SYNTHESIS OF KETO ACIDS OR AMINO ACIDS BY HYDRATION OF ACETYLENE COMPOUND | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2009-08-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140200349-A1 | Manganese Containing Hydrosilylation Catalysts and Compositions Containing the Catalysts | HIRA, MMS19, ALG8 | KCNH2 3972/4885POLB 618/4885NPSR1 3620/4885 |
| US-20140231702-A1 | Cobalt Containing Hydrosilylation Catalysts and Compositions Containing the Catalysts | HIRA, CROCC, GYPA | KCNH2 4374/4885POLB 1180/4885NPSR1 3825/4885 |
| US-20140183398-A1 | Nickel Containing Hydrosilylation Catalysts and Compositions Containing the Catalysts | HIRA, ALG8, CAD | KCNH2 4026/4885POLB 1428/4885NPSR1 2421/4885 |
| US-20140182483-A1 | Titanium Containing Hydrosilylation Catalysts And Compositions Containing The Catalysts | ITGA1, TMT1A, ITGA2 | KCNH2 4461/4885POLB 1126/4885NPSR1 2923/4885 |
| US-20090216044-A1 | METHOD FOR SYNTHESIS OF KETO ACIDS OR AMINO ACIDS BY HYDRATION OF ACETYLENE COMPOUND | AADAT, BCAT2, BCAT1 | KCNH2 150/4885POLB 3155/4885NPSR1 2026/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.