SCHEMBL4197277

SCHEMBL4197277

CC(=O)Oc1ccccc1B(O)O

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ENPP2 Q13822 1/20 0.57
PTGS2 P35354 8/20 0.55
KDM4E B2RXH2 2/20 0.55
HSD17B10 Q99714 2/20 0.55
ALDH1A1 P00352 1/20 0.55
ESR1 P03372 1/20 0.55
ITGB3 P05106 1/20 0.55
ITGA2B P08514 1/20 0.55
HMGB1 P09429 1/20 0.55
HPGD P15428 1/20 0.55
TSHR P16473 1/20 0.55
GGT1 P19440 1/20 0.55
PTGS1 P23219 1/20 0.55
BLM P54132 1/20 0.55
NAPRT Q6XQN6 1/20 0.55
TDP1 Q9NUW8 1/20 0.55
LMNA P02545 1/20 0.49
CYP1A2 P05177 1/20 0.49
CYP2C9 P11712 1/20 0.49
LIPE Q05469 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL338196 0.82 PTGS2 (0.68) PTGS2KDM4EHSD17B10ALDH1A1ESR1
SCHEMBL29432883 0.82 PTGS2 (0.68) PTGS2KDM4EHSD17B10ALDH1A1ESR1
Iodide SCHEMBL30619798 0.80 PTGS2 (0.65) PTGS2KDM4EHSD17B10ALDH1A1ESR1
Ethylene SCHEMBL28225928 0.78 PTGS2 (0.63) PTGS2KDM4EHSD17B10ALDH1A1ESR1
SCHEMBL31364528 0.77 THRB (0.50) ENPP2KDM4EHSD17B10ESR1HPGD
SCHEMBL16987295 0.77 THRB (0.50) ENPP2KDM4EHSD17B10ESR1HPGD
SCHEMBL17727042 0.76 ENPP2 (0.48) ENPP2KDM4EHSD17B10ALDH1A1HPGD
SCHEMBL8676653 0.76 PTGS2 (0.61) PTGS2KDM4EHSD17B10ALDH1A1ESR1
SCHEMBL10496464 0.76 PTGS2 (0.61) PTGS2KDM4EHSD17B10ALDH1A1ESR1
SCHEMBL4444465 0.76 HTT (0.61) PTGS2KDM4EHSD17B10ALDH1A1ESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4720728-A1 COATED SILICONE HYDROGEL CONTACT LENSES AND METHOD FOR MAKING THE SAME Alcon Inc. (CH) 2026-04-08 EP disclosed
US-12441750-B2 Organic metal complex, organic light-emitting device including the same, display apparatus, imaging apparatus, electronic apparatus, illumination apparatus, and moving object CANON KABUSHIKI KAISHA (JP) 2025-10-14 US disclosed
WO-2024241239-A1 COATED SILICONE HYDROGEL CONTACT LENSES AND METHOD FOR MAKING THE SAME ALCON INC. (CH) 2024-11-28 WO disclosed
US-20240393501-A1 COATED SILICONE HYDROGEL CONTACT LENSES AND METHOD FOR MAKING THE SAME ALCON INC (CH) 2024-11-28 US disclosed
US-11931454-B2 Wet-packed soft hydrogel ocular inserts ALCON INC. (CH) 2024-03-19 US disclosed
US-20220306666-A1 ORGANIC METAL COMPLEX, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME, DISPLAY APPARATUS, IMAGING APPARATUS, ELECTRONIC APPARATUS, ILLUMINATION APPARATUS, AND MOVING OBJECT CANON KABUSHIKI KAISHA (JP) 2022-09-29 US disclosed
CN-114727954-A Wet packed soft hydrogel ocular inserts 爱尔康公司 2022-07-08 CN disclosed
EP-4017478-A1 WET-PACKED SOFT HYDROGEL OCULAR INSERTS Alcon Inc. (CH) 2022-06-29 EP disclosed
WO-2021053586-A1 WET-PACKED SOFT HYDROGEL OCULAR INSERTS ALCON INC. (CH) 2021-03-25 WO disclosed
US-20210077385-A1 WET-PACKED SOFT HYDROGEL OCULAR INSERTS ALCON INC. (CH) 2021-03-18 US disclosed
US-7521581-B2 Catalyst composition and process for producing cross-coupled compound using same TOSOH CORPORATION (JP) 2009-04-21 US disclosed
EP-1707263-B1 Catalyst composition comprising an alkylene diamine-nickel complex and process for producing a cross-coupled compound using the same TOSOH CORP (JP) 2009-02-25 EP disclosed
US-20060224011-A1 Catalyst composition and process for producing cross-coupled compound using same TOSOH CORPORATION 2006-10-05 US disclosed
EP-1707263-A1 Catalyst composition comprising an alkylene diamine-nickel complex and process for producing a cross-coupled compound using the same Tosoh Corporation (JP) 2006-10-04 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210077385-A1 WET-PACKED SOFT HYDROGEL OCULAR INSERTS BRI3BP, BRWD1, HRH2 ENPP2 3807/4885PTGS2 959/4885KDM4E 2965/4885
US-20220306666-A1 ORGANIC METAL COMPLEX, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME, DISPLAY APPARATUS, IMAGING APPARATUS, ELECTRONIC APPARATUS, ILLUMINATION APPARATUS, AND MOVING OBJECT MSL1, MLX, L1CAM ENPP2 4275/4885PTGS2 4551/4885KDM4E 2857/4885
US-20060224011-A1 Catalyst composition and process for producing cross-coupled compound using same C5, TST, PYM1 ENPP2 1338/4885PTGS2 3696/4885KDM4E 2967/4885
US-12441750-B2 Organic metal complex, organic light-emitting device including the same, display apparatus, imaging apparatus, electronic apparatus, illumination apparatus, and moving object MSL1, MLX, L1CAM ENPP2 4275/4885PTGS2 4551/4885KDM4E 2857/4885
US-11931454-B2 Wet-packed soft hydrogel ocular inserts BRI3BP, BRWD1, HRH2 ENPP2 3807/4885PTGS2 959/4885KDM4E 2965/4885
US-20240393501-A1 COATED SILICONE HYDROGEL CONTACT LENSES AND METHOD FOR MAKING THE SAME CRYAB, P4HB, ILK ENPP2 4594/4885PTGS2 1288/4885KDM4E 441/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.