Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 6/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.40 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.40 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4202584 | 0.81 | RAB9A (0.51) | POLBNPC1HTTRAB9ASMN1; SMN2 | |
| SCHEMBL4186735 | 0.77 | ALOX15 (0.65) | KMT2ATP53 | |
| SCHEMBL4203660 | 0.76 | TMPRSS4 (0.56) | MEN1KMT2ACA12CA1CA2 | |
| SCHEMBL23246094 | 0.76 | RAB9A (0.55) | NPC1RAB9ASMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL4198230 | 0.76 | ALOX15 (0.63) | POLBNPC1RAB9ARXFP1ALDH1A1 | |
| SCHEMBL169574 | 0.75 | ALOX15 (0.47) | HTTRAB9ASMN1; SMN2ALDH1A1GAA | |
| SCHEMBL561714 | 0.75 | ALDH1A1 (0.47) | ALDH1A1MEN1KMT2A | |
| SCHEMBL4199011 | 0.74 | NPC1 (0.53) | POLBNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL6003847 | 0.74 | NPC1 (0.57) | NPC1HTTRAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL4201444 | 0.73 | ALOX15 (0.51) | HTTRAB9ASMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090088463-A1 | Pyrazoles Useful in the Treatment of Inflammation | BIOLIPOX AB (SE) | 2009-04-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090088463-A1 | Pyrazoles Useful in the Treatment of Inflammation | ALOX15, ALOX5, ALOX15B | POLB 2613/4885NPC1 2317/4885HTT 4152/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.