Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | PTAFR | P25105 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | KIF11 | P52732 | 3/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.32 |
| ▸ | RXRA | P19793 | 1/20 | 0.31 |
| ▸ | RXRB | P28702 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.31 |
| ▸ | HTR1D | P28221 | 1/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.30 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4198923 | 0.83 | PTAFR (0.34) | TSHRPTAFRALDH1A1NPC1RAB9A | |
| SCHEMBL4203318 | 0.82 | PSMB5 (0.38) | TSHRALDH1A1MAPTLMNASMN1; SMN2 | |
| SCHEMBL29594761 | 0.81 | BRD4 (0.36) | TSHRPTAFRALDH1A1MAPTNPC1 | |
| SCHEMBL1807786 | 0.81 | BRD4 (0.36) | TSHRPTAFRALDH1A1MAPTNPC1 | |
| SCHEMBL28148566 | 0.80 | BRD4 (0.36) | TSHRPTAFRALDH1A1MAPTNPC1 | |
| Lithium SCHEMBL30438304 | 0.80 | BRD4 (0.36) | TSHRPTAFRALDH1A1MAPTNPC1 | |
| SCHEMBL29949127 | 0.80 | ALDH1A1 (0.33) | ALDH1A1MAPTNPC1RAB9ARXRA | |
| SCHEMBL14645967 | 0.80 | ALDH1A1 (0.33) | ALDH1A1MAPTNPC1RAB9ARXRA | |
| SCHEMBL29040664 | 0.80 | BRD4 (0.36) | TSHRPTAFRALDH1A1MAPTNPC1 | |
| Hydrochloric Acid SCHEMBL27911650 | 0.79 | KIF11 (0.36) | TSHRPTAFRALDH1A1MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2746289-B1 | Catalysts | BOREALIS AG (AT) | 2017-09-27 | — | — | EP | disclosed |
| US-9469699-B2 | Catalysts | BOREALIS AG (AT) | 2016-10-18 | — | — | US | disclosed |
| US-20160002369-A1 | CATALYSTS | BOREALIS AG (AT) | 2016-01-07 | — | — | US | disclosed |
| CN-104870461-A | Catalyst and process for preparing same | BOREALIS AG | 2015-08-26 | — | — | CN | disclosed |
| WO-2014096164-A1 | CATALYSTS | BOREALIS AG (AT) | 2014-06-26 | — | — | WO | disclosed |
| EP-2746289-A1 | Catalysts | Borealis AG (AT) | 2014-06-25 | — | — | EP | disclosed |
| EP-1636245-B1 | BISINDENYL ZIRCONIUM COMPLEXES FOR USE IN THE POLYMERISATION OF OLEFINS | BASELL POLYOLEFINE GMBH (DE) | 2009-02-25 | — | — | EP | disclosed |
| US-20060252637-A1 | Bisindenyl zirconium complexes for use in the polymerization of olefins | BASELL POLYOLEFINE GMBH (DE) | 2006-11-09 | — | — | US | disclosed |
| EP-1636245-A1 | BISINDENYL ZIRCONIUM COMPLEXES FOR USE IN THE POLYMERISATION OF OLEFINS | Basell Polyolefine GmbH (DE) | 2006-03-22 | — | — | EP | disclosed |
| WO-2004106351-A1 | BISINDENYL ZIRCONIUM COMPLEXES FOR USE IN THE POLYMERISATION OF OLEFINS | BASELL POLYOLEFINE GMBH (DE) | 2004-12-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160002369-A1 | CATALYSTS | SIGMAR1, SFN, AP3S1 | TSHR 719/4885PTAFR 3871/4885ALDH1A1 2476/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.