Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.53 |
| ▸ | AKR1C1 | Q04828 | 3/20 | 0.53 |
| ▸ | LRRK2 | Q5S007 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.50 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.49 |
| ▸ | PTGES | O14684 | 1/20 | 0.49 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.48 |
| ▸ | KCNK10 | P57789 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.48 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6352462 | 0.90 | AKR1C2 (0.68) | GPR132AKR1C2AKR1C1AKR1C4AKR1C3 | |
| SCHEMBL6351828 | 0.88 | PTGES (0.62) | RAB9AAKR1C2AKR1C1NPC1MEN1 | |
| SCHEMBL4217129 | 0.87 | AKR1C2 (0.54) | RAB9AAKR1C2AKR1C1NPC1MEN1 | |
| SCHEMBL4208795 | 0.82 | NR4A2 (0.62) | RAB9AAKR1C2AKR1C1LRRK2NPC1 | |
| SCHEMBL4213146 | 0.82 | AKR1C2 (0.61) | RAB9AAKR1C2AKR1C1LRRK2NPC1 | |
| SCHEMBL6349385 | 0.80 | AKR1C2 (0.71) | RAB9AAKR1C2AKR1C1NPC1MEN1 | |
| SCHEMBL4209179 | 0.80 | AKR1C2 (0.56) | RAB9AAKR1C2AKR1C1NPC1MEN1 | |
| SCHEMBL4211236 | 0.80 | MAPT (0.59) | RAB9AAKR1C2AKR1C1LRRK2NPC1 | |
| SCHEMBL4206544 | 0.80 | NR4A2 (0.64) | RAB9AAKR1C2AKR1C1NPC1SMN1; SMN2 | |
| SCHEMBL6358257 | 0.79 | MAOB (0.58) | AKR1C2AKR1C1MEN1KMT2AAKR1C4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090247637-A1 | Novel Anthranilic Acid Derivatives | DEHMLOW HENRIETTA | 2009-10-01 | — | — | US | claimed |
| US-20050113450-A1 | Antibacterial agents | PHARMACIA & UPJOHN COMPANY | 2005-05-26 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050113450-A1 | Antibacterial agents | CLPP, SPOUT1, SAMHD1 | GPR132 4507/4885RAB9A 3062/4885AKR1C2 3012/4885 |
| US-20090247637-A1 | Novel Anthranilic Acid Derivatives | GPR84, GPR88, HCAR1 | GPR132 28/4885RAB9A 1445/4885AKR1C2 1087/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.