SCHEMBL422650

SCHEMBL422650

COc1cc(O)cc(Br)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.50
PTGS2 P35354 4/20 0.47
ALOX5 P09917 2/20 0.47
CYP1A1 P04798 2/20 0.47
CYP1B1 Q16678 2/20 0.47
TTR P02766 1/20 0.47
ALDH1A1 P00352 2/20 0.46
TP53 P04637 2/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
KDM4E B2RXH2 2/20 0.46
CALM1 P0DP23 2/20 0.46
MEN1 O00255 1/20 0.46
USP2 O75604 1/20 0.46
MAPT P10636 1/20 0.46
HPGD P15428 1/20 0.46
KMT2A Q03164 1/20 0.46
TRPV1 Q8NER1 1/20 0.46
HSD17B10 Q99714 1/20 0.46
CA1 P00915 1/20 0.45
CA2 P00918 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31443776 1.00 CYP3A4 (0.50) CYP3A4PTGS2ALOX5CYP1A1CYP1B1
SCHEMBL309832 0.82 ALDH1A1 (0.59) CYP3A4PTGS2ALOX5CYP1A1CYP1B1
SCHEMBL202288 0.82 ALDH1A1 (0.69) CYP3A4PTGS2ALOX5CYP1A1CYP1B1
SCHEMBL233829 0.82 ALDH1A1 (0.69) CYP3A4PTGS2ALOX5CYP1A1CYP1B1
Flamenol SCHEMBL69428 0.82 CYP3A4 (0.62) CYP3A4PTGS2ALOX5CYP1A1CYP1B1
SCHEMBL29051042 0.80 GABRA1 (0.56) CYP3A4PTGS2ALOX5CYP1A1CYP1B1
Flamenol SCHEMBL3190965 0.79 CYP3A4 (0.59) CYP3A4PTGS2ALOX5CYP1A1CYP1B1
SCHEMBL3966378 0.79 ALDH1A1 (0.65) CYP3A4PTGS2ALOX5CYP1A1CYP1B1
SCHEMBL2999328 0.79 ALDH1A1 (0.65) CYP3A4PTGS2ALOX5CYP1A1CYP1B1
SCHEMBL17204044 0.76 GABRA1 (0.39) CYP3A4PTGS2ALOX5ALDH1A1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 88 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116478199-A Bimetallic catalyst and preparation method thereof, and preparation method of high molecular weight olefin polymer 万华化学集团股份有限公司 2023-07-25 CN claimed
US-10029992-B2 Diaminotriazine compounds and their use as herbicides BASF SE (DE) 2018-07-24 US claimed
EP-3134391-A1 DIAMINOTRIAZINE COMPOUNDS AND THEIR USE AS HERBICIDES BASF SE (DE) 2017-03-01 EP claimed
US-20170044114-A1 Diaminotriazine compounds and their use as herbicides BASF SE (DE) 2017-02-16 US claimed
WO-2015162166-A1 DIAMINOTRIAZINE COMPOUNDS AND THEIR USE AS HERBICIDES BASF SE (DE) 2015-10-29 WO claimed
US-20050043369-A1 Bactericidal antimicrobial methods and compositions for use in treating gram positive infections PROTEZ PHARMACEUTICALS INC. (US) 2005-02-24 US claimed
US-20030225126-A1 Bactericidal antimicrobial methods and compositions for use in treating gram positive infections INFLUX, INC. 2003-12-04 US claimed
EP-1296688-A2 BACTERICIDAL ANTIMICROBIAL METHODS AND COMPOSITIONS FOR USE IN TREATING GRAM POSITIVE INFECTIONS COMPRISING AN ANTIBIOTIC POTENTIATOR HAVING ACYL HYDRAZIDE, OXY AMIDE OR 8-HYDROXY QUINOLINE STRUCTURE Influx, Inc. (US) 2003-04-02 EP claimed
WO-2001070213-A2 BACTERICIDAL ANTIMICROBIAL METHODS AND COMPOSITIONS FOR USE IN TREATING GRAM POSITIVE INFECTIONS COMPRISING AN ANTIBIOTIC POTENTIATOR HAVING ACYL HYDRAZIDE OXY AMIDE OR 8-HYDROXY QUINOLINE STRUCTURE INFLUX, INC. (US) 2001-09-27 WO claimed
EP-4747247-A1 NOVEL FATTY ACID AMIDE HYDROLASE MODULATORS, COMPOSITIONS COMPRISING THE SAME AND USES THEREOF Apogee Pharmaceuticals, Inc. (CA) 2026-05-27 EP disclosed
EP-4735423-A1 KV7 MODULATORS Saniona A/S (DK) 2026-05-06 EP disclosed
US-12459883-B2 Substituted hydroxystilbene compounds and derivatives synthesis and uses thereof Kynan Duke IP, LLC (US) 2025-11-04 US disclosed
US-12410137-B2 Fatty acid amide hydrolase modulators, compositions comprising the same and uses thereof APOGEE PHARMACEUTICALS, INC. (CA) 2025-09-09 US disclosed
US-20250129027-A1 FATTY ACID AMIDE HYDROLASE MODULATORS, COMPOSITIONS COMPRISING THE SAME AND USES THEREOF APOGEE PHARMACEUTICALS, INC. (CA) 2025-04-24 US disclosed
WO-2007034325-A1 CARBOXAMIDE DERIVATIVES AS MUSCARINIC RECEPTOR ANTAGONISTS PFIZER LIMITED (GB) 2007-03-29 WO disclosed
US-20050043369-A1 Bactericidal antimicrobial methods and compositions for use in treating gram positive infections PROTEZ PHARMACEUTICALS INC. (US) 2005-02-24 US disclosed
US-20030225126-A1 Bactericidal antimicrobial methods and compositions for use in treating gram positive infections INFLUX, INC. 2003-12-04 US disclosed
EP-1296688-A2 BACTERICIDAL ANTIMICROBIAL METHODS AND COMPOSITIONS FOR USE IN TREATING GRAM POSITIVE INFECTIONS COMPRISING AN ANTIBIOTIC POTENTIATOR HAVING ACYL HYDRAZIDE, OXY AMIDE OR 8-HYDROXY QUINOLINE STRUCTURE Influx, Inc. (US) 2003-04-02 EP disclosed
WO-2001070213-A2 BACTERICIDAL ANTIMICROBIAL METHODS AND COMPOSITIONS FOR USE IN TREATING GRAM POSITIVE INFECTIONS COMPRISING AN ANTIBIOTIC POTENTIATOR HAVING ACYL HYDRAZIDE OXY AMIDE OR 8-HYDROXY QUINOLINE STRUCTURE INFLUX, INC. (US) 2001-09-27 WO disclosed
US-3959388-A Preparation of phloroglucinol or its monomethyl ether ANDENO B.V. (NL) 1976-05-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030225126-A1 Bactericidal antimicrobial methods and compositions for use in treating gram positive infections NAAA, TLR8, OPA1 CYP3A4 2103/4885PTGS2 1384/4885ALOX5 817/4885
US-20250129027-A1 FATTY ACID AMIDE HYDROLASE MODULATORS, COMPOSITIONS COMPRISING THE SAME AND USES THEREOF FAAH, FAAH2, MGLL CYP3A4 654/4885PTGS2 249/4885ALOX5 20/4885
US-12410137-B2 Fatty acid amide hydrolase modulators, compositions comprising the same and uses thereof FAAH, FAAH2, MGLL CYP3A4 654/4885PTGS2 249/4885ALOX5 20/4885
US-10029992-B2 Diaminotriazine compounds and their use as herbicides NR4A3, CBR3, RCOR3 CYP3A4 2369/4885PTGS2 2846/4885ALOX5 4204/4885
US-12459883-B2 Substituted hydroxystilbene compounds and derivatives synthesis and uses thereof CYP8B1, HSD11B1, HSD11B2 CYP3A4 119/4885PTGS2 213/4885ALOX5 161/4885
US-20050043369-A1 Bactericidal antimicrobial methods and compositions for use in treating gram positive infections NAAA, TLR8, OPA1 CYP3A4 2103/4885PTGS2 1384/4885ALOX5 817/4885
US-20170044114-A1 Diaminotriazine compounds and their use as herbicides NR4A3, CBR3, RCOR3 CYP3A4 2402/4885PTGS2 2869/4885ALOX5 4230/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.