Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.50 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 6/20 | 0.49 |
| ▸ | CA1 | P00915 | 3/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | TAOK1 | Q7L7X3 | 2/20 | 0.47 |
| ▸ | TAOK3 | Q9H2K8 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | ADAMTS5 | Q9UNA0 | 2/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | MMP8 | P22894 | 1/20 | 0.47 |
| ▸ | MMP12 | P39900 | 1/20 | 0.47 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.46 |
| ▸ | FOLH1 | Q04609 | 5/20 | 0.46 |
| ▸ | DHFR | P00374 | 1/20 | 0.45 |
| ▸ | TYMS | P04818 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2249692 | 0.86 | CA2 (0.62) | TAS1R3TAS1R1CA2CA1CA12 | |
| SCHEMBL403968 | 0.85 | ADAMTS5 (0.58) | TAS1R3TAS1R1CA2CA1CA12 | |
| SCHEMBL7740201 | 0.83 | CA2 (0.54) | CA2CA1CA12CA9FOLH1 | |
| SCHEMBL7740198 | 0.83 | CA2 (0.54) | CA2CA1CA12CA9FOLH1 | |
| SCHEMBL2249688 | 0.81 | MMP12 (0.61) | TAS1R3TAS1R1CA2CA1CA12 | |
| SCHEMBL3995785 | 0.79 | PTPN1 (0.65) | CA2CA1CA12CA9L3MBTL1 | |
| SCHEMBL1096615 | 0.79 | TAS1R3 (0.49) | TAS1R3TAS1R1CA2CA1TAOK1 | |
| SCHEMBL2252322 | 0.78 | CA2 (0.66) | CA2CA1CA12CA9NPC1 | |
| SCHEMBL8237305 | 0.78 | CA2 (0.66) | CA2CA1CA12CA9NPC1 | |
| SCHEMBL403032 | 0.78 | TAS1R3 (0.50) | TAS1R3TAS1R1CA2CA1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090247506-A1 | Antibacterial agents | CHIRON CORPORATION | 2009-10-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090247506-A1 | Antibacterial agents | MRPL21, SI, PGLS | TAS1R3 4169/4885TAS1R1 3477/4885CA2 3457/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.