Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 known ✓ | P22748 | 1/20 | 0.31 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2511007 | 1.00 | APP (0.34) | APPEPHX2CA4 | |
| Potassium Ion SCHEMBL514903 | 0.98 | APP (0.35) | APPEPHX2 | |
| Potassium Ion SCHEMBL514904 | 0.98 | APP (0.35) | APPEPHX2 | |
| Lithium Ion SCHEMBL28840842 | 0.96 | APP (0.34) | APPEPHX2 | |
| Potassium Ion SCHEMBL11801337 | 0.93 | EPHX2 (0.41) | APPEPHX2 | |
| Potassium Ion SCHEMBL16010565 | 0.91 | EPHX2 (0.43) | APPEPHX2 | |
| Potassium Ion SCHEMBL16009058 | 0.91 | EPHX2 (0.43) | APPEPHX2 | |
| SCHEMBL4162092 | 0.89 | CA4 (0.33) | CA4 | |
| SCHEMBL676893 | 0.89 | CA4 (0.33) | CA4 | |
| Potassium Ion SCHEMBL5050696 | 0.86 | PTGS1 (0.31) | EPHX2CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8617711-B2 | Single layer film and hydrophilic material comprising the same | MITSUI CHEMICALS, INC. (JP) | 2013-12-31 | — | — | US | disclosed |
| US-20090191373-A1 | Single Layer Film and Hydrophilic Material Comprising the Same | MITSUI CHEMICALS ,INC. | 2009-07-30 | — | — | US | disclosed |
| EP-1955782-A1 | SINGLE LAYER FILM AND HYDROPHILIC MATERIAL COMPOSED OF SAME | Mitsui Chemicals, Inc. (JP) | 2008-08-13 | — | — | EP | disclosed |