Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 known ✓ | P22748 | 1/20 | 0.31 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4251605 | 1.00 | APP (0.34) | APPEPHX2CA4 | |
| Potassium Ion SCHEMBL514903 | 0.98 | APP (0.35) | APPEPHX2 | |
| Potassium Ion SCHEMBL514904 | 0.98 | APP (0.35) | APPEPHX2 | |
| Lithium Ion SCHEMBL28840842 | 0.96 | APP (0.34) | APPEPHX2 | |
| Potassium Ion SCHEMBL11801337 | 0.93 | EPHX2 (0.41) | APPEPHX2 | |
| Potassium Ion SCHEMBL16010565 | 0.91 | EPHX2 (0.43) | APPEPHX2 | |
| Potassium Ion SCHEMBL16009058 | 0.91 | EPHX2 (0.43) | APPEPHX2 | |
| SCHEMBL4162092 | 0.89 | CA4 (0.33) | CA4 | |
| SCHEMBL676893 | 0.89 | CA4 (0.33) | CA4 | |
| Potassium Ion SCHEMBL5050696 | 0.86 | PTGS1 (0.31) | EPHX2CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130317131-A1 | POLYMERS AND NANOGEL MATERIALS AND METHODS FOR MAKING AND USING THE SAME | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2013-11-28 | — | — | US | claimed |
| US-20130203812-A1 | IONIC SILICONE HYDROGELS COMPRISING PHARMACEUTICAL AND/OR NUTRICEUTICAL COMPONENTS AND HAVING IMPROVED HYDROLYTIC STABILITY | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2013-08-08 | — | — | US | claimed |
| US-8501832-B2 | Polymeric compositions comprising at least one volume excluding polymer | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2013-08-06 | — | — | US | claimed |
| US-20120283353-A1 | MEDICAL DEVICES HAVING HOMOGENEOUS CHARGE DENSITY AND METHODS FOR MAKING SAME | JOHNSON & JOHNSON VISION CARE, INC. | 2012-11-08 | — | — | US | claimed |
| US-20120212703-A1 | POLYMERIC COMPOSITIONS COMPRISING AT LEAST ONE VOLUME EXCLUDING POLYMER | JOHNSON & JOHNSON VISION CARE, INC. | 2012-08-23 | — | — | US | claimed |
| US-20070056900-A1 | Use of copolymers containing n-vinyl lactam for producing functionalized membranes | BASF AKTIENGESELLSCHAFT (DE) | 2007-03-15 | — | — | US | claimed |
| EP-3970970-B1 | RETROREFLECTIVE SHEET, USE AND PRODUCTION METHOD | KIWA CHEMICAL IND CO LTD (JP) | 2023-08-23 | — | — | EP | disclosed |
| US-20220155501-A1 | RETROREFLECTIVE SHEET | KIWA CHEMICAL INDUSTRY CO., LTD. (JP) | 2022-05-19 | — | — | US | disclosed |
| EP-3521371-B1 | METHOD FOR PRODUCING SEMI-IPN COMPOSITE | DAINIPPON INK & CHEMICALS (JP) | 2021-06-16 | — | — | EP | disclosed |
| US-10836902-B2 | Method for producing semi-IPN composite | DIC CORPORATION (JP) | 2020-11-17 | — | — | US | disclosed |
| US-10603876-B2 | Flexible display apparatus | SAMSUNG SDI CO., LTD. (KR) | 2020-03-31 | — | — | US | disclosed |
| US-10476037-B2 | Flexible display apparatus | SAMSUNG SDI CO., LTD. (KR) | 2019-11-12 | — | — | US | disclosed |
| EP-3521371-A1 | METHOD FOR PRODUCING SEMI-IPN COMPOSITE | DIC Corporation (JP) | 2019-08-07 | — | — | EP | disclosed |
| US-5342722-A | Blend of polyester and a styrene-acrylic copolymer | MITSUBISHI RAYON COMPANY LTD. (JP) | 1994-08-30 | — | — | US | disclosed |
| EP-0381457-B1 | Method of treating polyester fibers, polyester fibers treated by said method, and composite composed of said polyester fibers and nitrile group-containing highly saturated copolymer rubber | NIPPON ZEON CO (JP) | 1994-06-15 | — | — | EP | disclosed |
| US-5286783-A | Adhesive for bonding fibers to rubber | NIPPON ZEON CO., LTD. (JP) | 1994-02-15 | — | — | US | disclosed |
| EP-0573705-A1 | Toner resin composition and process for preparing same | MITSUBISHI RAYON CO., LTD (JP) | 1993-12-15 | — | — | EP | disclosed |
| US-5122397-A | Bonding embedded fibers to nitrile rubber by vulcanization; hoses, ribbed belts | NIPPON ZEON CO., LTD. (JP) | 1992-06-16 | — | — | US | disclosed |
| US-4245992-A | Discharge printing process for cellulosic fabrics using a quaternary amine polymer | TORAY INDUSTRIES, INC. (JP) | 1981-01-20 | — | — | US | disclosed |
| US-3980622-A | Polymerizable emulsifying agent and application thereof | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JA) | 1976-09-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130203812-A1 | IONIC SILICONE HYDROGELS COMPRISING PHARMACEUTICAL AND/OR NUTRICEUTICAL COMPONENTS AND HAVING IMPROVED HYDROLYTIC STABILITY | IGFBP6, IGFBP1, IGFBP2 | CA4 3609/4885APP 2139/4885EPHX2 3724/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.