Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.54 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.52 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.52 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.52 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.52 |
| ▸ | CHRM4 | P08173 | 5/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | FAAH | O00519 | 1/20 | 0.48 |
| ▸ | CNR2 | P34972 | 1/20 | 0.48 |
| ▸ | LTA4H | P09960 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4246343 | 0.90 | MEN1 (0.55) | CHRM4FAAHSMN1; SMN2MEN1KMT2A | |
| SCHEMBL4247834 | 0.90 | GRIN2D (0.52) | DGAT1CHRM4MAPTSMN1; SMN2KMT2A | |
| SCHEMBL4245175 | 0.85 | FAAH (0.58) | CHRM4MAPTALDH1A1FAAHSMN1; SMN2 | |
| SCHEMBL4239342 | 0.85 | SMN1; SMN2 (0.63) | MAPTALDH1A1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL5165692 | 0.85 | ADAMTS5 (0.60) | CHRM4MAPTALDH1A1FAAHNPC1 | |
| SCHEMBL5182248 | 0.84 | SMN1; SMN2 (0.51) | CHRM4MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4244741 | 0.83 | SLC6A5 (0.53) | CHRM4SMN1; SMN2MEN1KMT2ASLC6A5 | |
| SCHEMBL12813411 | 0.82 | TP53 (0.51) | CHRNB2CHRNA5CHRNA7CHRNA4CHRM4 | |
| SCHEMBL5526237 | 0.82 | CXCR3 (0.54) | CHRM4MAPTALDH1A1FAAHCNR2 | |
| SCHEMBL5526242 | 0.82 | CXCR3 (0.54) | CHRM4MAPTALDH1A1FAAHCNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090170901-A1 | Benzoyl Urea Derivatives | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 2009-07-02 | — | — | US | disclosed |
| EP-1771429-A1 | NEW BENZOYL UREA DERIVATIVES | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 2007-04-11 | — | — | EP | disclosed |
| WO-2006010966-A1 | NEW BENZOYL UREA DERIVATIVES | Richter Gedeon Vegyészeti Gyár Rt. (HU) | 2006-02-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090170901-A1 | Benzoyl Urea Derivatives | OPRM1, GRIN2C, GRIN3A | DGAT1 4235/4885CHRNB2 249/4885CHRNA5 69/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.