Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNRHR | P30968 | 20/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4253402 | 0.94 | GNRHR (1.00) | GNRHR | |
| Hydrochloric Acid SCHEMBL6644800 | 0.93 | GNRHR (0.99) | GNRHR | |
| SCHEMBL1642713 | 0.93 | GNRHR (1.00) | GNRHR | |
| Sufugolix SCHEMBL209021 | 0.92 | GNRHR (1.00) | GNRHR | |
| Hydrochloric Acid SCHEMBL1644350 | 0.92 | GNRHR (0.99) | GNRHR | |
| Sufugolix SCHEMBL4251869 | 0.92 | GNRHR (0.99) | GNRHR | |
| SCHEMBL6644404 | 0.92 | GNRHR (0.87) | GNRHR | |
| SCHEMBL8009377 | 0.91 | GNRHR (1.00) | GNRHR | |
| SCHEMBL799481 | 0.91 | GNRHR (0.83) | GNRHR | |
| SCHEMBL4053272 | 0.90 | GNRHR (0.94) | GNRHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090048273-A1 | PREMATURE OVULATION PREVENTIVE AGENT | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-02-19 | — | — | US | disclosed |
| US-20080207524-A1 | MEDICINAL PREPARATIONS FOR TREATING SEX HORMONE-DEPENDENT DISEASES | TAKEDA PHARMACEUTICAL COMPANY LIMITED | 2008-08-28 | — | — | US | disclosed |
| EP-1917978-A1 | PREMATURE OVULATION PREVENTIVE AGENT | Takeda Pharmaceutical Company Limited (JP) | 2008-05-07 | — | — | EP | disclosed |
| US-20050250793-A1 | Preventives/remedies for hot flash | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2005-11-10 | — | — | US | disclosed |
| EP-1495768-A1 | PREVENTIVES/REMEDIES FOR HOTFLASH | Takeda Pharmaceutical Company Limited (JP) | 2005-01-12 | — | — | EP | disclosed |
| US-20040116522-A1 | Medicinal solutions | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2004-06-17 | — | — | US | disclosed |
| EP-1163244-B1 | THIENOPYRIMIDINE COMPOUNDS, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2004-03-10 | — | — | EP | disclosed |
| EP-1393747-A1 | PREVENTIVES/REMEDIES FOR ALZHEIMER'S DISEASE | Takeda Chemical Industries, Ltd. (JP) | 2004-03-03 | — | — | EP | disclosed |
| US-20040034039-A1 | Solid preparations | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2004-02-19 | — | — | US | disclosed |
| US-20040023987-A1 | Sustained release compositions | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2004-02-05 | — | — | US | disclosed |
| EP-1374855-A1 | MEDICINAL SOLUTIONS | Takeda Chemical Industries, Ltd. (JP) | 2004-01-02 | — | — | EP | disclosed |
| US-20030176360-A1 | Medicinal preparations for treating sex hormone-dependent diseases | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2003-09-18 | — | — | US | disclosed |
| US-20030134863-A1 | Preventives/remedies for alzheimer's disease | TAKEDA CHEMICAL INDUSTRIES LTD. (JP) | 2003-07-17 | — | — | US | disclosed |
| EP-1319409-A1 | SOLID PREPARATIONS | Takeda Chemical Industries, Ltd. (JP) | 2003-06-18 | — | — | EP | disclosed |
| EP-1297850-A1 | MEDICINAL PREPARATIONS FOR TREATING SEX HORMONE-DEPENDENT DISEASES | Takeda Chemical Industries, Ltd. (JP) | 2003-04-02 | — | — | EP | disclosed |
| EP-1291023-A1 | SUSTAINED RELEASE COMPOSITIONS | Takeda Chemical Industries, Ltd. (JP) | 2003-03-12 | — | — | EP | disclosed |
| US-6340686-B1 | GONADOTROPIN-RELEASING HORMONE ANTAGONISTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2002-01-22 | — | — | US | disclosed |
| US-6297379-B1 | GONADOTROPIN RELEASING HORMONE (GNRH, SOMETIMES CALLED LH-RH (LUTEINIZING HORMONE RELEASING HORMONE)) ANTAGONIZING ACTIVITY, TREATING SEX HORMONE-DEPENDENT DISEASES. | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-10-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030134863-A1 | Preventives/remedies for alzheimer's disease | ACHE, GNRHR, PSEN1 | GNRHR 2/4885 |
| US-20080207524-A1 | MEDICINAL PREPARATIONS FOR TREATING SEX HORMONE-DEPENDENT DISEASES | SHBG, GNRHR, NR5A1 | GNRHR 2/4885 |
| US-20040023987-A1 | Sustained release compositions | NGLY1, GHSR, GHRHR | GNRHR 46/4885 |
| US-20050250793-A1 | Preventives/remedies for hot flash | GNRHR, SHBG, FSHR | GNRHR 1/4885 |
| US-20040034039-A1 | Solid preparations | GYS1, GYS2, SI | GNRHR 3501/4885 |
| US-20090048273-A1 | PREMATURE OVULATION PREVENTIVE AGENT | GNRHR, FSHR, LHCGR | GNRHR 1/4885 |
| US-20030176360-A1 | Medicinal preparations for treating sex hormone-dependent diseases | SHBG, GNRHR, NR5A1 | GNRHR 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.