Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR3 | P46089 | 1/20 | 0.50 |
| ▸ | IDO1 | P14902 | 7/20 | 0.48 |
| ▸ | TDO2 | P48775 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | LIMK1 | P53667 | 2/20 | 0.41 |
| ▸ | IKBKB | O14920 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.40 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.39 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.39 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12145585 | 0.77 | LIMK1 (0.50) | GPR3IDO1TDO2ALDH1A1MAPT | |
| SCHEMBL1518983 | 0.76 | GPR3 (0.55) | GPR3TDO2ALDH1A1MAPTHPGD | |
| SCHEMBL29434786 | 0.76 | GPR3 (0.55) | GPR3TDO2ALDH1A1MAPTHPGD | |
| SCHEMBL3769911 | 0.76 | GPR3 (0.55) | GPR3IDO1TDO2ALDH1A1MAPT | |
| SCHEMBL309376 | 0.76 | GPR3 (0.55) | GPR3TDO2ALDH1A1MAPTHPGD | |
| Iodide SCHEMBL30577896 | 0.74 | GPR3 (0.52) | GPR3IDO1TDO2ALDH1A1MAPT | |
| SCHEMBL19135547 | 0.74 | GPR3 (0.52) | GPR3ALDH1A1MAPTHPGDRAB9A | |
| Hydrochloric Acid SCHEMBL9404602 | 0.74 | GPR3 (0.52) | GPR3IDO1TDO2ALDH1A1MAPT | |
| SCHEMBL24442088 | 0.73 | GPR3 (0.50) | GPR3TDO2ALDH1A1MAPTHPGD | |
| SCHEMBL718497 | 0.73 | GPR3 (0.50) | GPR3IDO1ALDH1A1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110016058-B | Metal complex, organic electroluminescent material and organic electroluminescent device | 石家庄诚志永华显示材料有限公司 | 2021-11-05 | — | — | CN | disclosed |
| WO-2020153758-A1 | COMPOSITION, ORGANIC OPTOELECTRONIC DIODE, AND DISPLAY DEVICE | 엘티소재주식회사 | 2020-07-30 | — | — | WO | disclosed |
| US-10414762-B2 | Amides of acetic and propionic acids | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2019-09-17 | — | — | US | disclosed |
| CN-110016058-A | Metal complex, electroluminescent organic material, organic electroluminescence device | 北京诚志永华显示科技有限公司 | 2019-07-16 | — | — | CN | disclosed |
| US-20190010150-A1 | AMIDES OF ACETIC AND PROPIONIC ACIDS | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2019-01-10 | — | — | US | disclosed |
| US-9914729-B2 | Amides of acetic and propionic acids | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2018-03-13 | — | — | US | disclosed |
| US-20170183339-A1 | AMIDES OF ACETIC AND PROPIONIC ACIDS | BAYER HEALTHCARE AG (DE) | 2017-06-29 | — | — | US | disclosed |
| US-20170141325-A1 | HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING SAME | HEESUNG MATERIAL LTD. (KR) | 2017-05-18 | — | — | US | disclosed |
| US-20170141325-A1 | HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING SAME | HEESUNG MATERIAL LTD. (KR) | 2017-05-18 | — | — | US | disclosed |
| EP-3162806-A2 | HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING SAME | Heesung Material Ltd. (KR) | 2017-05-03 | — | — | EP | disclosed |
| US-20110284799-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2011-11-24 | — | — | US | disclosed |
| US-20110284799-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2011-11-24 | — | — | US | disclosed |
| WO-2010086089-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2010-08-05 | — | — | WO | disclosed |
| US-20090258898-A1 | AMIDES OF ACETIC AND PROPIONIC ACIDS | BAYER HEALTHCARE AG (DE) | 2009-10-15 | — | — | US | disclosed |
| US-7553851-B2 | Amides of acetic and propionic acids | BAYER HEALTHCARE AG (DE) | 2009-06-30 | — | — | US | disclosed |
| US-20070037844-A1 | 2-(1-Azabicyclo[2.2.2]oct-3-yl)-N-(7-bromo-1-benzothien-2-yl)acetamide hydrochloride; nicotinic receptor agonists; cognition activators; learning enhancement; nootropic agents; demetia; cholinergic agents; Alzheimer's disease; brain traumas; stroke; attention deficit disorder; schizophrenia | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2007-02-15 | — | — | US | disclosed |
| EP-1487835-B1 | AMIDES OF ACETIC AND PROPIONIC ACIDS | BAYER HEALTHCARE AG (DE) | 2006-09-20 | — | — | EP | disclosed |
| WO-2005044008-A2 | 2 -AMINOTHIOPHENE COMPOUNDS AS FUNGICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2005-05-19 | — | — | WO | disclosed |
| EP-1487835-A1 | AMIDES OF ACETIC AND PROPIONIC ACIDS | Bayer Aktiengesellschaft (DE) | 2004-12-22 | — | — | EP | disclosed |
| WO-2003078430-A1 | AMIDES OF ACETIC AND PROPIONIC ACIDS | BAYER HEALTHCARE AG (DE) | 2003-09-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170183339-A1 | AMIDES OF ACETIC AND PROPIONIC ACIDS | HCAR2, HCAR3, NAAA | GPR3 262/4885IDO1 1490/4885TDO2 3580/4885 |
| US-20110284799-A1 | METAL COMPLEXES | SOD1, AP1M1, AP3M1 | GPR3 4376/4885IDO1 2782/4885TDO2 2590/4885 |
| US-20190010150-A1 | AMIDES OF ACETIC AND PROPIONIC ACIDS | HCAR2, HCAR3, NAAA | GPR3 262/4885IDO1 1490/4885TDO2 3580/4885 |
| US-20090258898-A1 | AMIDES OF ACETIC AND PROPIONIC ACIDS | HCAR2, HCAR3, NAAA | GPR3 262/4885IDO1 1490/4885TDO2 3580/4885 |
| US-20070037844-A1 | 2-(1-Azabicyclo[2.2.2]oct-3-yl)-N-(7-bromo-1-benzothien-2-yl)acetamide hydrochloride; nicotinic receptor agonists; cognition activators; learning enhancement; nootropic agents; demetia; cholinergic agents; Alzheimer's disease; brain traumas; stroke; attention deficit disorder; schizophrenia | CHRNA2, CHRNA6, CHRNA5 | GPR3 468/4885IDO1 1859/4885TDO2 3087/4885 |
| US-20170141325-A1 | HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING SAME | CRY1, CRY2, CYBA | GPR3 3579/4885IDO1 2175/4885TDO2 606/4885 |
| US-10414762-B2 | Amides of acetic and propionic acids | HCAR2, HCAR3, NAAA | GPR3 262/4885IDO1 1490/4885TDO2 3580/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.