SCHEMBL4293075

SCHEMBL4293075

COc1ccc(-c2coc3c(OC)c(O)ccc3c2=O)cc1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.69
MEN1 O00255 6/20 0.69
KMT2A Q03164 6/20 0.69
CYP3A4 P08684 5/20 0.69
MAPT P10636 5/20 0.69
SMN1; SMN2 Q16637 5/20 0.69
TP53 P04637 4/20 0.69
LMNA P02545 2/20 0.69
THRB P10828 1/20 0.69
MAPK1 P28482 2/20 0.61
KDM4E B2RXH2 5/20 0.60
CYP2D6 P10635 3/20 0.60
CYP2C9 P11712 3/20 0.60
CYP2C19 P33261 3/20 0.60
HPGD P15428 3/20 0.60
MAOA P21397 2/20 0.60
MAOB P27338 2/20 0.60
CYP1B1 Q16678 2/20 0.60
HSD17B10 Q99714 2/20 0.60
BCL2 P10415 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19097319 0.91 XDH (0.68) ALDH1A1MEN1KMT2ACYP3A4MAPT
SCHEMBL19110926 0.90 ALOX15 (0.71) ALDH1A1MEN1KMT2ACYP3A4MAPT
SCHEMBL2070030 0.88 ALDH1A1 (0.79) ALDH1A1MEN1KMT2ACYP3A4MAPT
SCHEMBL29929767 0.88 ALDH1A1 (0.79) ALDH1A1MEN1KMT2ACYP3A4MAPT
SCHEMBL2070701 0.87 ALDH1A1 (0.69) ALDH1A1MEN1KMT2ACYP3A4MAPT
SCHEMBL29503823 0.86 ALDH1A1 (0.67) ALDH1A1MEN1KMT2ACYP3A4MAPT
SCHEMBL28451821 0.86 ALDH1A1 (0.67) ALDH1A1MEN1KMT2ACYP3A4MAPT
SCHEMBL571373 0.85 MAPT (0.74) ALDH1A1MEN1KMT2ACYP3A4MAPT
SCHEMBL30903606 0.85 KDM4E (0.70) ALDH1A1MEN1KMT2ACYP3A4MAPT
SCHEMBL18222918 0.85 KDM4E (0.70) ALDH1A1MEN1KMT2ACYP3A4MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders YEWSAVIN INC (US) 2026-01-15 US disclosed
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders YewSavin, Inc. (US) 2025-07-01 US disclosed
WO-2024233598-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2024-11-14 WO disclosed
EP-4429763-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS Yewsavin, Inc. (US) 2024-09-18 EP disclosed
WO-2023086388-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-05-19 WO disclosed
CN-111560000-B Synthesis method of polyhydroxy isoflavone 中国人民解放军联勤保障部队第九〇四医院 2022-04-12 CN disclosed
CN-111560000-A Synthesis method of polyhydroxy isoflavone 中国人民解放军联勤保障部队第九〇四医院 2020-08-21 CN disclosed
US-8557331-B2 Antifouling method and composition using chromen-4-one derivatives THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) 2013-10-15 US disclosed
US-20110177237-A1 ANTIFOULING METHOD AND COMPOSITION USING CHROMEN-4-ONE DERIVATIVES THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) 2011-07-21 US disclosed
US-20100305068-A1 COMPOUNDS AND METHODS FOR MODULATING PROTEIN TRAFFICKING FOLDRX PHARMACEUTICALS, INC. (US) 2010-12-02 US disclosed
US-20100305068-A1 COMPOUNDS AND METHODS FOR MODULATING PROTEIN TRAFFICKING FOLDRX PHARMACEUTICALS, INC. (US) 2010-12-02 US disclosed
US-20090143279-A1 Methods and compositions for treating metabolic disorders PRESIDENT AND FELLOWS OF HARVARD COLLEGE 2009-06-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100305068-A1 COMPOUNDS AND METHODS FOR MODULATING PROTEIN TRAFFICKING GOLT1B, NPC1L1, NPC1 ALDH1A1 3582/4885MEN1 3909/4885KMT2A 4369/4885
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders SERPINC1, F2, F13B ALDH1A1 3285/4885MEN1 3367/4885KMT2A 2792/4885
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders SERPINC1, SERPINE1, SERPINH1 ALDH1A1 3081/4885MEN1 2457/4885KMT2A 3188/4885
US-20090143279-A1 Methods and compositions for treating metabolic disorders PC, PCK2, CS ALDH1A1 860/4885MEN1 3749/4885KMT2A 2380/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.