SCHEMBL4307692

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4312120	0.78	CHKA (0.32)	LMNAMAPTCYP19A1CHKASIGMAR1
	SCHEMBL28266689	0.72	LMNA (0.36)	LMNAMAPTMEN1KMT2AHDAC8
	SCHEMBL4306573	0.72	ESR1 (0.46)	LMNAMAPTMEN1KMT2AHDAC8
	SCHEMBL28282637	0.72	LMNA (0.36)	LMNAMAPTMEN1KMT2AHDAC8
	SCHEMBL27881636	0.72	LMNA (0.36)	LMNAMAPTMEN1KMT2AHDAC8
	SCHEMBL23215085	0.72	OPRL1 (0.42)	LMNAMAPTALDH1A1CYP19A1HSD11B1
	SCHEMBL2894741	0.72	LMNA (0.39)	LMNAMAPTMEN1KMT2AALDH1A1
	SCHEMBL14943252	0.72	CYP19A1 (0.38)	LMNAMAPTHDAC8CYP19A1CHKA
	SCHEMBL659326	0.70	ESR1 (0.54)	LMNAMAPTALDH1A1CYP19A1CHKA
	SCHEMBL17469412	0.69	EPHX2 (0.41)	LMNAMAPTCYP2D6TSHRCYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.