Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.39 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.39 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL43607 | 0.86 | HCAR2 (0.38) | TDP1HCAR2ALDH1A1 | |
| SCHEMBL587685 | 0.80 | GAA (0.47) | GAATSHRTDP1RAB9ASMPD1 | |
| SCHEMBL43819 | 0.79 | GABRA1 (0.33) | HCAR2ALDH1A1 | |
| SCHEMBL43967 | 0.79 | HCAR2 (0.59) | TDP1SMN1; SMN2L3MBTL1HCAR2ALDH1A1 | |
| SCHEMBL10073623 | 0.76 | MMP3 (0.44) | GAATSHRTDP1RAB9ASMPD1 | |
| SCHEMBL11844391 | 0.75 | GAA (0.51) | GAATSHRTDP1RAB9ASMPD1 | |
| SCHEMBL29883142 | 0.75 | TSHR (0.45) | GAATSHRTDP1RAB9ANPC1 | |
| SCHEMBL9784740 | 0.75 | RAB9A (0.49) | RAB9AHTTSMN1; SMN2MAOBL3MBTL1 | |
| SCHEMBL3292009 | 0.74 | ALDH1A1 (0.58) | GAATSHRTDP1RAB9ASMPD1 | |
| SCHEMBL114536 | 0.74 | GAA (0.54) | GAATSHRTDP1RAB9ASMPD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011157444-A1 | FUNCTIONALIZED MATERIALS BY CATALYZED CARBENE COPOLYMERIZATION | STICHTING DUTCH POLYMER INSTITUTE (NL) | 2011-12-22 | — | — | WO | disclosed |