Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 5/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 5/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 4/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 4/20 | 0.33 |
| ▸ | GABRA3 | P34903 | 4/20 | 0.33 |
| ▸ | GABRA2 | P47869 | 4/20 | 0.33 |
| ▸ | GABRA4 | P48169 | 4/20 | 0.33 |
| ▸ | GABRA6 | Q16445 | 3/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.32 |
| ▸ | MET | P08581 | 1/20 | 0.32 |
| ▸ | TGM2 | P21980 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | GABRP | O00591 | 2/20 | 0.31 |
| ▸ | GABRD | O14764 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL43607 | 0.80 | HCAR2 (0.38) | HCAR2LMNAFFAR1METTGM2 | |
| SCHEMBL43077 | 0.79 | GAA (0.44) | HCAR2ALDH1A1 | |
| SCHEMBL43368 | 0.79 | ALDH1A1 (0.51) | GABRA1GABRA5GABRG2GABRB3GABRA3 | |
| SCHEMBL18641309 | 0.77 | GABRA1 (0.37) | GABRA1GABRA5GABRG2GABRB3GABRA3 | |
| SCHEMBL707570 | 0.74 | MET (0.36) | HCAR2LMNAMETTGM2CYP1A2 | |
| SCHEMBL43967 | 0.74 | HCAR2 (0.59) | HCAR2LMNATGM2CYP1A2CYP2C9 | |
| SCHEMBL9784740 | 0.70 | RAB9A (0.49) | POLBALDH1A1 | |
| SCHEMBL1710488 | 0.69 | NOS3 (0.38) | GABRA1GABRA5GABRG2GABRB3GABRA3 | |
| SCHEMBL4212601 | 0.69 | FFAR1 (0.50) | GABRA1GABRA5GABRG2GABRB3GABRA3 | |
| SCHEMBL3447198 | 0.69 | FFAR1 (0.65) | LMNAFFAR1ALDH1A1AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011157444-A1 | FUNCTIONALIZED MATERIALS BY CATALYZED CARBENE COPOLYMERIZATION | STICHTING DUTCH POLYMER INSTITUTE (NL) | 2011-12-22 | — | — | WO | disclosed |