SCHEMBL432074

SCHEMBL432074

CCCCCCCCCCCCCCCCCCCCCC(=O)NC(CC)(NC(=O)CCCCCCCCCCCCCCCCCCCCC)N(C)C

nearest known ligand 0.50

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
HSP90AA1 P07900 1/20 0.50
DNM1 Q05193 3/20 0.49
FAAH O00519 6/20 0.48
HRH3 Q9Y5N1 1/20 0.47
ALDH1A1 P00352 1/20 0.46
MEN1 O00255 1/20 0.46
MAPK1 P28482 1/20 0.46
KMT2A Q03164 1/20 0.46
CES2 O00748 3/20 0.42
CES1 P23141 3/20 0.42
TRPV1 Q8NER1 3/20 0.41
POLB P06746 1/20 0.41
POLA1 P09884 1/20 0.41
CNR1 P21554 1/20 0.41
CNR2 P34972 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL116063 0.98 HSP90AA1 (0.48) HSP90AA1DNM1FAAHHRH3ALDH1A1
SCHEMBL28487707 0.91 HRH3 (0.62) FAAHHRH3MEN1KMT2APOLB
SCHEMBL428924 0.87 HRH3 (0.58) HRH3ALDH1A1MEN1KMT2ATRPV1
Bromide SCHEMBL8773079 0.83 HRH3 (0.57) FAAHHRH3MEN1KMT2APOLB
Hydrochloric Acid SCHEMBL10397331 0.79 DNM1 (0.51) HSP90AA1DNM1FAAHHRH3ALDH1A1
SCHEMBL29053617 0.76 HSP90AA1 (0.55) HSP90AA1FAAHHRH3ALDH1A1MEN1
SCHEMBL496957 0.76 HSP90AA1 (0.55) HSP90AA1FAAHHRH3ALDH1A1MEN1
SCHEMBL5592299 0.76 ALDH1A1 (0.66) HSP90AA1FAAHHRH3ALDH1A1MEN1
SCHEMBL115462 0.75 FAAH (0.53) HSP90AA1DNM1FAAHHRH3ALDH1A1
SCHEMBL23378025 0.75 HSP90AA1 (0.59) HSP90AA1FAAHHRH3ALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116891421-A Eutectic mixture containing salicylic acid 株式会社LG生活健康 2023-10-17 CN disclosed
WO-2019109243-A1 Cosmetic composition for permanently changing the shape of keratinous fibers HENKEL AG & CO.KGAA (DE) 2019-06-13 WO disclosed
EP-2393469-B1 Process of treating hair RHODIA OPERATIONS (FR) 2016-10-12 EP disclosed
US-20120021025-A1 AQUEOUS COMPOSITION SUITABLE AS SHAMPOO RHODIA OPERATIONS (FR) 2012-01-26 US disclosed
EP-2337544-A2 USE OF MATRIX METALLOPROTEINASE INHIBITORS IN SKIN CARE Living Proof, Inc. (US) 2011-06-29 EP disclosed
WO-2010089228-A9 AQUEOUS COMPOSITION SUITABLE AS SHAMPOO RHODIA OPERATIONS (FR) 2011-04-21 WO disclosed
WO-2010089228-A1 AQUEOUS COMPOSITION SUITABLE AS SHAMPOO RHODIA OPERATIONS (FR) 2010-08-12 WO disclosed
EP-2216010-A1 Aqueous composition suitable as shampoo Rhodia Opérations (FR) 2010-08-11 EP disclosed
US-20100143274-A1 USE OF AMINES AND AMIDES FOR THE STABILIZATION OF ORGANIC MICRONIZED UV ABSORBERS CIBA CORPORATION (US) 2010-06-10 US disclosed
EP-2120846-A2 USE OF AMINES AND AMIDES FOR THE STABILIZATION OF ORGANIC MICRONIZED UV ABSORBERS BASF SE (DE) 2009-11-25 EP disclosed
US-6958148-B1 Linkage of agents to body tissue using microparticles and transglutaminase PERICOR SCIENCE, INC. (US) 2005-10-25 US disclosed
US-6919076-B1 Conjugates of agents and transglutaminase substrate linking molecules PERICOR SCIENCE, INC. (US) 2005-07-19 US disclosed
US-20040170587-A1 Method of compatibilizing cationic materials with anionic polymers LUBRIZOL ADVANCED MATERIALS, INC. 2004-09-02 US disclosed
US-20040052748-A1 Compositions of anionic polymeric rheology modifiers and cationic materials LUBRIZOL ADVANCED MATERIALS, INC. 2004-03-18 US disclosed
EP-1303260-A2 LINKAGE OF AGENTS USING MICROPARTICLES Pericor Science, Inc. (US) 2003-04-23 EP disclosed
EP-1203141-A1 LINKAGE OF AGENTS TO TISSUE Pericor Science, Inc. (US) 2002-05-08 EP disclosed
EP-1202706-A1 LYSINE OXIDASE LINKAGE OF AGENTS TO TISSUE Pericor Science, Inc. (US) 2002-05-08 EP disclosed
WO-2002007707-A2 LINKAGE OF AGENTS USING MICROPARTICLES PERICOR SCIENCE, INC. (US) 2002-01-31 WO disclosed
WO-2001007009-A1 LYSINE OXIDASE LINKAGE OF AGENTS TO TISSUE PERICOR SCIENCE, INC. (US) 2001-02-01 WO disclosed
WO-2001006829-A2 LINKAGE OF AGENTS TO TISSUE PERICOR SCIENCE, INC. (US) 2001-02-01 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100143274-A1 USE OF AMINES AND AMIDES FOR THE STABILIZATION OF ORGANIC MICRONIZED UV ABSORBERS MAOA, MAOB, ACMSD HSP90AA1 1225/4885DNM1 2231/4885FAAH 243/4885
US-20040170587-A1 Method of compatibilizing cationic materials with anionic polymers PARN, PARG, PICALM HSP90AA1 2865/4885DNM1 1070/4885FAAH 4478/4885
US-20040052748-A1 Compositions of anionic polymeric rheology modifiers and cationic materials PBRM1, PARG, PARN HSP90AA1 4282/4885DNM1 1791/4885FAAH 4299/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.