SCHEMBL428924

SCHEMBL428924

CCCCC/C=C\C/C=C\CCCCCCCC(=O)NC(CC)(NC(=O)CCCCCCC/C=C\C/C=C\CCCCC)N(C)C

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HRH3 Q9Y5N1 1/20 0.58
MEN1 O00255 2/20 0.57
KMT2A Q03164 2/20 0.57
ALDH1A1 P00352 5/20 0.56
HPGD P15428 3/20 0.56
CNR1 P21554 2/20 0.56
TDP1 Q9NUW8 2/20 0.56
TRPV1 Q8NER1 1/20 0.56
MAPT P10636 1/20 0.56
ALOX12 P18054 1/20 0.56
BLM P54132 1/20 0.56
F7 P08709 2/20 0.54
F3 P13726 2/20 0.54
DUSP3 P51452 1/20 0.54
PTPN7 P35236 1/20 0.54
KDM4E B2RXH2 1/20 0.54
FFAR1 O14842 1/20 0.54
LMNA P02545 1/20 0.54
FABP3 P05413 1/20 0.54
CYP3A4 P08684 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28487707 0.96 HRH3 (0.62) HRH3MEN1KMT2AMAPTBLM
Bromide SCHEMBL8773079 0.88 HRH3 (0.57) HRH3MEN1KMT2AMAPTBLM
SCHEMBL432074 0.87 HSP90AA1 (0.50) HRH3MEN1KMT2AALDH1A1CNR1
Hydrochloric Acid SCHEMBL116063 0.85 HSP90AA1 (0.48) HRH3MEN1KMT2AALDH1A1CNR1
SCHEMBL22461508 0.81 HRH3 (0.66) HRH3MEN1KMT2AALDH1A1HPGD
SCHEMBL11731139 0.80 HRH3 (0.64) HRH3MEN1KMT2AALDH1A1HPGD
SCHEMBL11755295 0.78 HRH3 (0.58) HRH3MEN1KMT2ATDP1MAPT
SCHEMBL11139957 0.78 MEN1 (0.77) MEN1KMT2AALDH1A1HPGDCNR1
SCHEMBL16626967 0.78 MEN1 (0.63) HRH3MEN1KMT2AALDH1A1HPGD
SCHEMBL27447674 0.78 HRH3 (0.69) HRH3MEN1KMT2AALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 568 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260144726-A1 POLYOL-FREE COSMETIC COMPOSITION COMPRISING ALPHA HYDROXY ACID ESTER L'OREAL (FR) 2026-05-28 US claimed
US-20260108440-A1 Personal Care Compositions COLGATE-PALMOLIVE COMPANY (US) 2026-04-23 US claimed
EP-4719612-A1 RINSE-OFF HAIR COSMETIC COMPOSITIONS, METHOD OF TREATING HAIR, METHOD FOR PROVIDING IMPROVED CURLS DEFINITION TO THE HAIR AND USE OF A COMPOSITION L'OREAL (FR) 2026-04-08 EP claimed
US-20260060909-A1 HAIR CARE COMPOSITION COMPRISING TERTIARY AMIDOAMINES SURFACTANT (TAS), SALICYLIC ACID, FREE OF FATTY ALCOHOL AND PH= 6.5 L'OREAL (FR) 2026-03-05 US claimed
US-20260047988-A1 HAIR COSMETIC COMPOSITIONS AND METHOD OF TREATING HAIR L'OREAL (FR) 2026-02-19 US claimed
EP-4633589-A1 HAIR TREATMENT COMPOSITIONS THAT IMPART SHINE AND LUSTER L'OREAL (FR) 2025-10-22 EP claimed
US-20250281376-A1 Hair Care Composition CORET JOEL MARCEL (US) 2025-09-11 US claimed
EP-4608516-A2 LONG WEAR NON-CRACKING COLOR COSMETIC COMPOSITIONS Revlon Consumer Products LLC (US) 2025-09-03 EP claimed
US-12377039-B2 Cleansing compositions L'OREAL (FR) 2025-08-05 US claimed
US-20250235396-A1 LONG WEAR NON-CRACKING COLOR COSMETIC COMPOSITIONS REVLON CONSUMER PRODUCTS CORPORATION 2025-07-24 US claimed
US-9186314-B2 Compositions and methods for sealing the surface of keratinous substrates L'OREAL (FR) 2015-11-17 US claimed
US-8795697-B2 Sanitizing composition and method of preparation BROWN JAMES S (US) 2014-08-05 US claimed
US-20130149274-A1 COMPOSITIONS AND METHODS FOR SEALING THE SURFACE OF KERATINOUS SUBSTRATES L'OREAL S.A. (FR) 2013-06-13 US claimed
WO-2012021472-A2 COMPOSITIONS AND METHODS FOR SEALING THE SURFACE OF KERATINOUS SUBSTRATES L'OREAL S. A. (FR) 2012-02-16 WO claimed
US-20100202988-A1 CLEAR CARRIER COMPOSITIONS CONTAINING AN ALKOXYLATED MONOACID AND AN ALKYL MONOAMINE AND METHOD OF TREATING KERATINOUS SUBSTRATES USING SUCH COMPOSITIONS L'OREAL (FR) 2010-08-12 US claimed
EP-1073511-A4 POLYMERIC DIFUNCTIONAL CATIONIC EMOLLIENTS AND CONDITIONERS FOR USE IN COSMETIC, PERSONAL CARE AND HOUSEHOLD PRODUCTS ALZO INC (US) 2005-08-03 EP claimed
US-20020155962-A1 Nonaqueous hair styling composition and method of use ANDREW JERGENS COMPANY, THE 2002-10-24 US claimed
EP-1073511-A1 POLYMERIC DIFUNCTIONAL CATIONIC EMOLLIENTS AND CONDITIONERS FOR USE IN COSMETIC, PERSONAL CARE AND HOUSEHOLD PRODUCTS Alzo, Inc. (US) 2001-02-07 EP claimed
US-6107352-A CLEANING COMPOUNDS; COSMETICS ALZO, INC. (US) 2000-08-22 US claimed
WO-1999054027-A1 POLYMERIC DIFUNCTIONAL CATIONIC EMOLLIENTS AND CONDITIONERS FOR USE IN COSMETIC, PERSONAL CARE AND HOUSEHOLD PRODUCTS ALZO, INC. (US) 1999-10-28 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260060909-A1 HAIR CARE COMPOSITION COMPRISING TERTIARY AMIDOAMINES SURFACTANT (TAS), SALICYLIC ACID, FREE OF FATTY ALCOHOL AND PH= 6.5 KRT18, ADH1A, ADH1C HRH3 249/4885MEN1 3620/4885KMT2A 2104/4885
US-20260144726-A1 POLYOL-FREE COSMETIC COMPOSITION COMPRISING ALPHA HYDROXY ACID ESTER HAO2, HADH, LDHA HRH3 188/4885MEN1 2466/4885KMT2A 2037/4885
US-20260047988-A1 HAIR COSMETIC COMPOSITIONS AND METHOD OF TREATING HAIR HCAR1, CUTA, HCAR3 HRH3 357/4885MEN1 4338/4885KMT2A 3164/4885
US-20250235396-A1 LONG WEAR NON-CRACKING COLOR COSMETIC COMPOSITIONS CUTA, RIOK1, RIOK2 HRH3 2264/4885MEN1 2399/4885KMT2A 685/4885
US-20260108440-A1 Personal Care Compositions PBDC1, PIEZO1, TRPC7 HRH3 2167/4885MEN1 3357/4885KMT2A 2504/4885
US-12377039-B2 Cleansing compositions SMURF1, SMURF2, SGMS2 HRH3 2741/4885MEN1 2591/4885KMT2A 3030/4885
US-20130149274-A1 COMPOSITIONS AND METHODS FOR SEALING THE SURFACE OF KERATINOUS SUBSTRATES KRT18, PLOD3, DDC HRH3 819/4885MEN1 3756/4885KMT2A 563/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.