Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | FAAH | O00519 | 2/20 | 0.41 |
| ▸ | NAAA | Q02083 | 1/20 | 0.41 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4334667 | 0.89 | NPC1 (0.49) | MAPTL3MBTL1SMN1; SMN2FFAR1ALDH1A1 | |
| SCHEMBL4342343 | 0.88 | FFAR1 (0.41) | MAPTL3MBTL1SMN1; SMN2FAAHFFAR1 | |
| SCHEMBL4332643 | 0.87 | CASP1 (0.42) | MAPTSMN1; SMN2NAAAASAH1ALDH1A1 | |
| SCHEMBL4334154 | 0.86 | LMNA (0.44) | MAPTL3MBTL1SMN1; SMN2FFAR1ALDH1A1 | |
| SCHEMBL4342514 | 0.85 | ALDH1A1 (0.42) | MAPTSMN1; SMN2FFAR1ALDH1A1CYP2C19 | |
| SCHEMBL4331854 | 0.85 | OPRM1 (0.44) | MAPTL3MBTL1 | |
| SCHEMBL4328963 | 0.84 | PTGDR2 (0.47) | FFAR1 | |
| SCHEMBL4339537 | 0.82 | HDAC1 (0.40) | L3MBTL1SMN1; SMN2FFAR1ALDH1A1CYP2C19 | |
| SCHEMBL4329063 | 0.82 | MAPT (0.49) | MAPTL3MBTL1FAAHNAAAASAH1 | |
| SCHEMBL4329058 | 0.82 | MAPT (0.49) | MAPTL3MBTL1FAAHNAAAASAH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7544835-B2 | Carboxylic acid derivative and salt thereof | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-06-09 | — | — | US | disclosed |