SCHEMBL432990

SCHEMBL432990

Clc1c(Br)ccc2[nH][c]cc12

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 1/20 0.32
HTR2C P28335 1/20 0.32
HTR2B P41595 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1065531 0.68 AHR (0.52)
SCHEMBL767109 0.65 NOS1 (0.55)
SCHEMBL4276905 0.65 CYP1A2 (0.46)
SCHEMBL9739407 0.65 KDM4E (0.40)
SCHEMBL28584478 0.65 HTR2A (0.41) HTR2AHTR2CHTR2B
SCHEMBL9742121 0.61 ALDH1A1 (0.34)
SCHEMBL14746132 0.61 RHEB (0.47)
Phosphoric Acid SCHEMBL6130379 0.61 AHR (0.43)
SCHEMBL208744 0.60 LMNA (0.51)
SCHEMBL1444295 0.60 ALDH1A1 (0.52)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8741593-B2 Method for releasing a product comprising chemical oxidation, method for detecting said product and uses thereof PROTEUS (FR) 2014-06-03 US claimed
EP-1285086-B1 METHOD FOR LIBERATING A PRODUCT COMPRISING A CHEMICAL OXYDATION, DETECTION OF THE PRODUCT AND FURTHER APPLICATIONS PROTEUS (FR) 2013-07-03 EP claimed
EP-1691779-A4 TREATMENT OF A CONDITION IN A MAMMAL WITH ADMINISTRATION OF COMPOUNDS AND METHODS OF USE THEREOF OPTIMER PHARMACEUTICALS INC (US) 2009-01-21 EP claimed
US-20070099257-A1 Method for releasing a product comprising chemical oxidation, method for detecting said product and uses thereof PROTEUS (FR) 2007-05-03 US claimed
US-20070082851-A1 Treatment of a condition in a mammal with administration of Compounds and Methods of Use OPTIMER PHARMACEUTICALS INC. (US) 2007-04-12 US claimed
EP-1691779-A2 TREATMENT OF A CONDITION IN A MAMMAL WITH ADMINISTRATION OF COMPOUNDS AND METHODS OF USE THEREOF Optimer Pharmaceuticals, Inc. (US) 2006-08-23 EP claimed
WO-2005051326-A2 TREATMENT OF A CONDITION IN A MAMMAL WITH ADMINISTRATION OF COMPOUNDS AND METHODS OF USE THEREOF OPTIMER PHARMACEUTICALS, INC. (US) 2005-06-09 WO claimed
US-20030199017-A1 Method for releasing a product comprising chemical oxidation, method for detecting said product and uses thereof PROTEUS 2003-10-23 US claimed
EP-1285086-A2 METHOD FOR DETECTING A DETECTABLE PRODUCT Proteus (FR) 2003-02-26 EP claimed
WO-2001092563-A2 METHOD FOR DETECTING A DETECTABLE PRODUCT PROTEUS (FR) 2001-12-06 WO claimed
EP-0495346-B1 Procedure for separation, identification, and quantification of isoenzymes and isoforms of the alkaline phosphatase ANALIS SA (BE) 1996-05-15 EP claimed
EP-2588219-B1 FILTER PLATE ARTICLE HAVING A WATER-ABSORBENT FILTER ASSEMBLY NEOGEN FOOD SAFETY US HOLDCO CORP (US) 2024-05-29 EP disclosed
US-11892450-B2 Evaluation, assays and treatment of pKal-mediated disorders TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2024-02-06 US disclosed
CN-116096240-A Lactic acid bacteria composition for preparing fermented food 科·汉森有限公司 2023-05-09 CN disclosed
US-11618880-B2 Compositions comprising bacterial strains and use thereof in controlling pathogenic microorganisms BETTER AIR INTERNATIONAL LIMITED (HK) 2023-04-04 US disclosed
US-5958675-A Method for detecting bacteria using bacteriophage, contrast-coloring dye and precipitable dye 3M INNOVATIVE PROPERTIES COMPANY (US) 1999-09-28 US disclosed
US-5843742-A Adeno-associated derived vector systems for gene delivery and integration into target cells AVIGEN INCORPORATED (US) 1998-12-01 US disclosed
WO-1998048042-A2 METHODS AND DEVICES FOR DETECTING BACTERIOPHAGE MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1998-10-29 WO disclosed
US-5292669-A Chromogenic agent, oxidizer BOEHRINGER MANNHEIM GMBH (DE) 1994-03-08 US disclosed
US-4327073-A IMMOBILIZATION AND USE OF RADIOACTIVE TRACERS KENDREW BIOSYSTEMS, INC., A CORP. OF DE 1982-04-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030199017-A1 Method for releasing a product comprising chemical oxidation, method for detecting said product and uses thereof CBR1, AOX1, MPO HTR2A 1170/4885HTR2C 788/4885HTR2B 570/4885
US-20070082851-A1 Treatment of a condition in a mammal with administration of Compounds and Methods of Use AADAT, MMP1, MMP13 HTR2A 1260/4885HTR2C 1775/4885HTR2B 1563/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.