SCHEMBL43302

SCHEMBL43302

N[C@@H](Cc1ccccc1Br)C(=O)O

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 3/20 0.58
PKM P14618 2/20 0.58
ALPI P09923 1/20 0.58
PTGS1 P23219 1/20 0.58
XIAP P98170 1/20 0.58
NOS3 P29474 3/20 0.57
NOS1 P29475 3/20 0.57
NOS2 P35228 3/20 0.57
MAPT P10636 3/20 0.51
KDM4E B2RXH2 2/20 0.51
MEN1 O00255 2/20 0.51
LMNA P02545 2/20 0.51
BLM P54132 2/20 0.51
PMP22 Q01453 2/20 0.51
KMT2A Q03164 2/20 0.51
HIF1A Q16665 2/20 0.51
MPO P05164 1/20 0.51
TSHR P16473 1/20 0.51
PPARG P37231 1/20 0.50
PPARA Q07869 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29400473 1.00 SLC7A5 (0.58) SLC7A5PKMALPIPTGS1XIAP
SCHEMBL1250588 1.00 SLC7A5 (0.58) SLC7A5PKMALPIPTGS1XIAP
SCHEMBL43301 1.00 SLC7A5 (0.58) SLC7A5PKMALPIPTGS1XIAP
SCHEMBL13971424 0.86 SLC7A5 (0.69) SLC7A5PKMALPIPTGS1XIAP
SCHEMBL9164980 0.86 SLC7A5 (0.69) SLC7A5PKMALPIPTGS1XIAP
SCHEMBL5301987 0.86 NOS3 (0.50) SLC7A5PKMALPIPTGS1XIAP
SCHEMBL2152873 0.85 NOS3 (0.45) SLC7A5PKMALPIPTGS1XIAP
SCHEMBL2152875 0.85 NOS3 (0.45) SLC7A5PKMALPIPTGS1XIAP
Hydrochloric Acid SCHEMBL9169793 0.84 SLC7A5 (0.67) SLC7A5PKMALPIPTGS1XIAP
SCHEMBL22289236 0.83 NOS3 (0.48) SLC7A5PKMALPIPTGS1XIAP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1595 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12590137-B2 Meditope-enabled T cells CITY OF HOPE (US) 2026-03-31 US claimed
US-20250066418-A1 CYSTEINE PEPTIDE-ENABLED ANTIBODIES CITY OF HOPE 2025-02-27 US claimed
US-20240425584-A1 MECHANICALLY INTERLOCKING COMPLEXES CITY OF HOPE 2024-12-26 US claimed
CN-118767648-A System for storing carbon dioxide, application and carbon dioxide storage and transportation method 中国石油化工股份有限公司 2024-10-15 CN claimed
CN-114457049-B Pyrrolysiyl-tRNA synthetase mutant and application thereof 浙江大学杭州国际科创中心 2024-09-24 CN claimed
US-12077611-B2 Cyclic peptides multimers targeting α4β7 integrin ZEALAND PHARMA A/S (DK) 2024-09-03 US claimed
US-11897952-B2 Mechanically interlocking complexes CITY OF HOPE 2024-02-13 US claimed
CN-117442748-A Multivalent mimotopes, mimotope binding antibodies and uses thereof 希望之城公司 2024-01-26 CN claimed
US-20230406884-A1 CYCLIC PEPTIDES MULTIMERS TARGETING ALPHA-4-BETA-7 INTEGRIN ZEALAND PHARMA A/S (DK) 2023-12-21 US claimed
US-20230391887-A1 MULTIVALENT MEDITOPES, MEDITOPE-BINDING ANTIBODIES AND USES THEREOF HOPE CITY (US) 2023-12-07 US claimed
EP-2069518-B1 METHOD FOR PRODUCING OPTICALLY ACTIVE PHENYLALANINE COMPOUNDS FROM CINNAMIC ACID DERIVATIVES EMPLOYING A PHENYLALANINE AMMONIA LYASE DERIVED FROM IDIOMARINA LOIHIENSIS DSM IP ASSETS BV (NL) 2010-02-03 EP claimed
US-7576175-B2 Amino acid terminated diphenylurea derivatives; display high binding affinity, specificity, and stability; use in treating cancer, inflammatory diseases, and autoimmune diseases THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2009-08-18 US claimed
US-7399619-B2 Site specific incorporation of heavy atom-containing unnatural amino acids into proteins for structure determination THE SCRIPPS RESEARCH INSTITUTE (US) 2008-07-15 US claimed
WO-2008031016-A2 HETEROCYCLIC LIGANDS FOR INTEGRIN IMAGING AND THERAPY THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2008-03-13 WO claimed
EP-1774018-A2 SITE SPECIFIC INCORPORATION OF HEAVY ATOM-CONTAINING UNNATURAL AMINO ACIDS INTO PROTEINS FOR CRYSTAL STRUCTURE DETERMINATION The Scripps Research Institute (US) 2007-04-18 EP claimed
WO-2005122379-A9 ALPHA-4 BETA-1 INTEGRIN LIGANDS FOR IMAGING AND THERAPY UNIV CALIFORNIA (US) 2006-03-09 WO claimed
US-20060019900-A1 Alpha-4 beta-1 integrin ligands for imaging and therapy THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2006-01-26 US claimed
WO-2005122379-A2 ALPHA-4 BETA-1 INTEGRIN LIGANDS FOR IMAGING AND THERAPY THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2005-12-22 WO claimed
US-20050272121-A1 Translation system including an orthogonal aminoacyl-transfer RNA synthetase with a specific sequence that preferentially aminoacylates an orthogonal transfer RNA with a brominated or iodinated phenylalanine or tyrosine THE SCRIPPS RESEARCH INSTITUTE (US) 2005-12-08 US claimed
WO-2005116237-A2 SITE SPECIFIC INCORPORATION OF HEAVY ATOM-CONTAINING UNNATURAL AMINO ACIDS INTO PROTEINS FOR CRYSTAL STRUCTURE DETERMINATION THE SCRIPPS RESEARCH INSTITUTE (US) 2005-12-08 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230391887-A1 MULTIVALENT MEDITOPES, MEDITOPE-BINDING ANTIBODIES AND USES THEREOF FCGR3B, FCGR2A, CD47 SLC7A5 3511/4885PKM 3363/4885ALPI 1470/4885
US-11897952-B2 Mechanically interlocking complexes FCGR3B, FCGR2A, FCGRT SLC7A5 2742/4885PKM 3560/4885ALPI 4028/4885
US-20250066418-A1 CYSTEINE PEPTIDE-ENABLED ANTIBODIES LNPEP, CSTB, PTMS SLC7A5 305/4885PKM 4362/4885ALPI 4850/4885
US-20050272121-A1 Translation system including an orthogonal aminoacyl-transfer RNA synthetase with a specific sequence that preferentially aminoacylates an orthogonal transfer RNA with a brominated or iodinated phenylalanine or tyrosine AARS1, NSUN3, TARBP1 SLC7A5 63/4885PKM 3547/4885ALPI 4410/4885
US-20060019900-A1 Alpha-4 beta-1 integrin ligands for imaging and therapy ITGA4, ITGB4, ITGA1 SLC7A5 576/4885PKM 4240/4885ALPI 3006/4885
US-12077611-B2 Cyclic peptides multimers targeting α4β7 integrin ITGB7, ITGB4, ITGA4 SLC7A5 2076/4885PKM 3336/4885ALPI 3864/4885
US-20240425584-A1 MECHANICALLY INTERLOCKING COMPLEXES FCGR3B, FCGR2A, FCGRT SLC7A5 2742/4885PKM 3560/4885ALPI 4028/4885
US-20230406884-A1 CYCLIC PEPTIDES MULTIMERS TARGETING ALPHA-4-BETA-7 INTEGRIN ITGB7, ITGB4, ITGA4 SLC7A5 2407/4885PKM 3794/4885ALPI 3773/4885
US-12590137-B2 Meditope-enabled T cells CD4, ICOS, CD40 SLC7A5 708/4885PKM 3225/4885ALPI 307/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.