Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 3/20 | 0.58 |
| ▸ | PKM | P14618 | 2/20 | 0.58 |
| ▸ | ALPI | P09923 | 1/20 | 0.58 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.58 |
| ▸ | XIAP | P98170 | 1/20 | 0.58 |
| ▸ | NOS3 | P29474 | 3/20 | 0.57 |
| ▸ | NOS1 | P29475 | 3/20 | 0.57 |
| ▸ | NOS2 | P35228 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | BLM | P54132 | 2/20 | 0.51 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.51 |
| ▸ | MPO | P05164 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | PPARG | P37231 | 1/20 | 0.50 |
| ▸ | PPARA | Q07869 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29400473 | 1.00 | SLC7A5 (0.58) | SLC7A5PKMALPIPTGS1XIAP | |
| SCHEMBL43302 | 1.00 | SLC7A5 (0.58) | SLC7A5PKMALPIPTGS1XIAP | |
| SCHEMBL1250588 | 1.00 | SLC7A5 (0.58) | SLC7A5PKMALPIPTGS1XIAP | |
| SCHEMBL13971424 | 0.86 | SLC7A5 (0.69) | SLC7A5PKMALPIPTGS1XIAP | |
| SCHEMBL9164980 | 0.86 | SLC7A5 (0.69) | SLC7A5PKMALPIPTGS1XIAP | |
| SCHEMBL5301987 | 0.86 | NOS3 (0.50) | SLC7A5PKMALPIPTGS1XIAP | |
| SCHEMBL2152873 | 0.85 | NOS3 (0.45) | SLC7A5PKMALPIPTGS1XIAP | |
| SCHEMBL2152875 | 0.85 | NOS3 (0.45) | SLC7A5PKMALPIPTGS1XIAP | |
| Hydrochloric Acid SCHEMBL9169793 | 0.84 | SLC7A5 (0.67) | SLC7A5PKMALPIPTGS1XIAP | |
| SCHEMBL22289236 | 0.83 | NOS3 (0.48) | SLC7A5PKMALPIPTGS1XIAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1250 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12454512-B2 | Processes and intermediates for the preparation of 2-(2,6-dichlorophenyl)-1-[(1S,3R)-3-(hydroxymethyl)-5-(3-hydroxy-3-methylbutyl)-1-methyl-3,4-dihydroisoquinolin-2(1H)-yl]ethenone | ELI LILLY AND COMPANY (US) | 2025-10-28 | — | — | US | claimed |
| CN-118767648-A | System for storing carbon dioxide, application and carbon dioxide storage and transportation method | 中国石油化工股份有限公司 | 2024-10-15 | — | — | CN | claimed |
| US-20230303647-A1 | CYCLIC CHEMERIN-9 DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 2023-09-28 | — | — | US | claimed |
| EP-3986867-B1 | PROCESSES AND INTERMEDIATES FOR THE PREPARATION OF 2-(2,6-DICHLOROPHENYL)-1-[(1S,3R)-3-(HYDROXYMETHYL)-5-(3-HYDROXY-3-METHYLBUTYL)-1-METHYL-3,4-DIHYDROISOQUINOLIN-2(1H)-YL]ETHENONE | LILLY CO ELI (US) | 2023-09-13 | — | — | EP | claimed |
| CN-116390742-A | Cyclic chemokine-9 derivatives | 拜耳公司 | 2023-07-04 | — | — | CN | claimed |
| EP-4196143-A1 | CYCLIC CHEMERIN-9 DERIVATIVES | Bayer Aktiengesellschaft (DE) | 2023-06-21 | — | — | EP | claimed |
| US-20220242826-A1 | PROCESSES AND INTERMEDIATES FOR THE PREPARATION OF 2-(2,6-DICHLOROPHENYL)-1-[(1S,3R)-3-(HYDROXYMETHYL)-5-(3-HYDROXY-3-METHYLBUTYL)-1-METHYL-3,4-DIHYDROISOQUINOLIN-2(1H)-YL]ETHENONE | ELI LILLY AND COMPANY | 2022-08-04 | — | — | US | claimed |
| WO-2022034057-A1 | CYCLIC CHEMERIN-9 DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 2022-02-17 | — | — | WO | claimed |
| CN-113993849-A | Processes and intermediates for the preparation of 2- (2, 6-dichlorophenyl) -1- [ (1S,3R) -3- (hydroxymethyl) -5- (3-hydroxy-3-methylbutyl) -1-methyl-3, 4-dihydroisoquinolin-2 (1H) -yl ] ketene | 伊莱利利公司 | 2022-01-28 | — | — | CN | claimed |
| US-20150299286-A1 | GLUTAMIC ACID-STABILIZED INSULIN ANALOGUES | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR NIH | 2015-10-22 | — | — | US | claimed |
| US-20090081669-A1 | Fluorescent Assays Using Orthogonal tRNA - Aminoacyl Synthetase Pairs | ENCODE BIO, INC. (US) | 2009-03-26 | — | — | US | claimed |
| WO-2008031016-A2 | HETEROCYCLIC LIGANDS FOR INTEGRIN IMAGING AND THERAPY | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2008-03-13 | — | — | WO | claimed |
| WO-2007090198-A2 | FLUORESCENT ASSAYS USING ORTHOGONAL TRNA - AMINOACYL SYNTHETASE PAIRS | ENCODE BIO, INC. (US) | 2007-08-09 | — | — | WO | claimed |
| US-20070178554-A1 | Orthogonal Aminoacyl Synthetase-tRNA Pairs for Incorporating Unnatural Amino Acids Into Proteins | NEURION PHARMACEUTICALS, INC. | 2007-08-02 | — | — | US | claimed |
| WO-2006039717-A2 | METHODS OF DETERMINING PRECISE HERG INTERACTIONS AND ALTERING COMPOUNDS BASED ON SAID INTERACTIONS | NEURION PHARMACEUTICALS, INC. (US) | 2006-04-13 | — | — | WO | claimed |
| WO-2005122379-A9 | ALPHA-4 BETA-1 INTEGRIN LIGANDS FOR IMAGING AND THERAPY | UNIV CALIFORNIA (US) | 2006-03-09 | — | — | WO | claimed |
| US-20060019900-A1 | Alpha-4 beta-1 integrin ligands for imaging and therapy | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2006-01-26 | — | — | US | claimed |
| US-20060014159-A1 | Methods of determining precise HERG interactions and designing compounds based on said interactions | NEURION PHARMACEUTICALS, INC. (US) | 2006-01-19 | — | — | US | claimed |
| WO-2005122379-A2 | ALPHA-4 BETA-1 INTEGRIN LIGANDS FOR IMAGING AND THERAPY | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2005-12-22 | — | — | WO | claimed |
| US-5658885-A | OLIGOPEPTIDES; ANTICOAGULANTS; ENZYME INHIBITORS; THROMBIN | THE DUPONT MERCK PHARMACEUTICAL COMPANY (US) | 1997-08-19 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060019900-A1 | Alpha-4 beta-1 integrin ligands for imaging and therapy | ITGA4, ITGB4, ITGA1 | SLC7A5 576/4885PKM 4240/4885ALPI 3006/4885 |
| US-12454512-B2 | Processes and intermediates for the preparation of 2-(2,6-dichlorophenyl)-1-[(1S,3R)-3-(hydroxymethyl)-5-(3-hydroxy-3-methylbutyl)-1-methyl-3,4-dihydroisoquinolin-2(1H)-yl]ethenone | PAM, TLR1, TLR2 | SLC7A5 4519/4885PKM 415/4885ALPI 2615/4885 |
| US-20060014159-A1 | Methods of determining precise HERG interactions and designing compounds based on said interactions | KCNN4, KCNC1, HCN4 | SLC7A5 810/4885PKM 4079/4885ALPI 4428/4885 |
| US-20230303647-A1 | CYCLIC CHEMERIN-9 DERIVATIVES | CMKLR1, CMKLR2, CCL2 | SLC7A5 3537/4885PKM 3023/4885ALPI 2013/4885 |
| US-20070178554-A1 | Orthogonal Aminoacyl Synthetase-tRNA Pairs for Incorporating Unnatural Amino Acids Into Proteins | AARS1, GARS1, TRMT1 | SLC7A5 171/4885PKM 3856/4885ALPI 2899/4885 |
| US-20220242826-A1 | PROCESSES AND INTERMEDIATES FOR THE PREPARATION OF 2-(2,6-DICHLOROPHENYL)-1-[(1S,3R)-3-(HYDROXYMETHYL)-5-(3-HYDROXY-3-METHYLBUTYL)-1-METHYL-3,4-DIHYDROISOQUINOLIN-2(1H)-YL]ETHENONE | PAM, TLR1, TLR2 | SLC7A5 4519/4885PKM 415/4885ALPI 2615/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.