Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | ELANE | P08246 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | LIG1 | P18858 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12710862 | 0.88 | KDM4E (0.47) | KDM4EELANELMNAALDH1A1PDE4B | |
| SCHEMBL15312851 | 0.84 | KDM4E (0.60) | KDM4EALDH1A1PDE4BGAATSHR | |
| SCHEMBL2972344 | 0.81 | GAA (0.60) | ELANELMNAALDH1A1GAAHPGD | |
| SCHEMBL23748267 | 0.80 | ALDH1A1 (0.58) | KDM4ELMNAALDH1A1GAAATM | |
| SCHEMBL22229873 | 0.80 | KDM4E (0.62) | KDM4ELMNAALDH1A1PDE4BGAA | |
| SCHEMBL9130664 | 0.80 | KDM4E (0.58) | KDM4ELMNAALDH1A1PDE4BGAA | |
| SCHEMBL16090170 | 0.80 | PTGDR2 (0.60) | LMNAALDH1A1HPGDCYP1A2CYP2D6 | |
| SCHEMBL13690626 | 0.78 | KDM4E (0.57) | KDM4EALDH1A1PDE4BGAATSHR | |
| SCHEMBL132849 | 0.78 | LIG1 (0.63) | KDM4EELANEGAATSHRHPGD | |
| SCHEMBL23748273 | 0.77 | LIG1 (0.51) | KDM4EALDH1A1GAATSHRHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11773207-B2 | Thiol compound, method for synthesizing same, and uses for said thiol compound | SHIKOKU CHEMICALS CORPORATION (JP) | 2023-10-03 | — | — | US | disclosed |
| US-11773207-B2 | Thiol compound, method for synthesizing same, and uses for said thiol compound | SHIKOKU CHEMICALS CORPORATION (JP) | 2023-10-03 | — | — | US | disclosed |
| WO-2020145111-A1 | THIOL COMPOUND, METHOD FOR SYNTHESIZING SAME, AND USES FOR SAID THIOL COMPOUND | 四国化成工業株式会社 | 2020-07-16 | — | — | WO | disclosed |
| US-7592143-B2 | Methods of treating diseases responsive to induction of apoptosis and screening assays | CYTOVIA, INC. (US) | 2009-09-22 | — | — | US | disclosed |
| EP-1620564-A4 | METHODS OF TREATING DISEASES RESPONSIVE TO INDUCTION OF APOPTOSIS AND SCREENING ASSAYS | CYTOVIA INC (US) | 2008-03-12 | — | — | EP | disclosed |
| EP-1620564-A2 | METHODS OF TREATING DISEASES RESPONSIVE TO INDUCTION OF APOPTOSIS AND SCREENING ASSAYS | Cytovia, Inc. (US) | 2006-02-01 | — | — | EP | disclosed |
| US-20050004026-A1 | Methods of treating diseases responsive to induction of Apoptosis and screening assays | CYTOVIA, INC. | 2005-01-06 | — | — | US | disclosed |
| WO-2004094647-A2 | METHODS OF TREATING DISEASES RESPONSIVE TO INDUCTION OF APOPTOSIS AND SCREENING ASSAYS | CYTOVIA, INC. (US) | 2004-11-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050004026-A1 | Methods of treating diseases responsive to induction of Apoptosis and screening assays | HEATR6, HEATR1, AIP | KDM4E 4490/4885ELANE 4448/4885LMNA 4586/4885 |
| US-11773207-B2 | Thiol compound, method for synthesizing same, and uses for said thiol compound | TST, TMT1A, CTH | KDM4E 1377/4885ELANE 748/4885LMNA 4474/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.