Sugi Predict

Sugi Predict / Compounds / SCHEMBL433468

SCHEMBL433468

SCHEMBL433468

CCOCC(O)(c1ccc(Cl)cc1)c1ccc(Cl)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ NPSR1 Q6W5P4 6/20 0.49
▸ MEN1 O00255 6/20 0.47
▸ KMT2A Q03164 6/20 0.47
▸ SMN1; SMN2 Q16637 2/20 0.47
▸ POLB P06746 1/20 0.47
▸ L3MBTL1 Q9Y468 1/20 0.47
▸ TSHR P16473 1/20 0.47
▸ MAPK1 P28482 1/20 0.47
▸ HIF1A Q16665 1/20 0.47
▸ BCL2 P10415 2/20 0.46
▸ LMNA P02545 5/20 0.44
▸ HTT P42858 4/20 0.44
▸ CYP1A2 P05177 1/20 0.40
▸ CYP3A4 P08684 1/20 0.40
▸ CYP2D6 P10635 1/20 0.40
▸ CYP2C9 P11712 1/20 0.40
▸ CYP2C19 P33261 1/20 0.40
▸ MIF P14174 1/20 0.40
▸ CYP19A1 P11511 1/20 0.40
▸ RECQL P46063 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15043684 0.80 GRIN2D (0.51) NPSR1MEN1KMT2ATSHRMAPK1
SCHEMBL662471 0.80 SMN1; SMN2 (0.44) MEN1KMT2ASMN1; SMN2MAPK1LMNA
SCHEMBL13131547 0.77 NPSR1 (0.57) NPSR1MEN1KMT2ASMN1; SMN2POLB
1,4-Dichlorobenzene SCHEMBL27933757 0.73 LMNA (0.50) MEN1KMT2ASMN1; SMN2POLBTSHR
SCHEMBL13539406 0.72 NPSR1 (0.67) NPSR1MEN1KMT2ASMN1; SMN2POLB
SCHEMBL7932610 0.71 NPSR1 (0.53) NPSR1MEN1KMT2ASMN1; SMN2POLB
SCHEMBL10786071 0.71 ESR1 (0.57) NPSR1MEN1KMT2ASMN1; SMN2POLB
SCHEMBL11625992 0.71 BCL2 (0.58) NPSR1MEN1KMT2ASMN1; SMN2POLB
SCHEMBL3884434 0.70 NPSR1 (0.53) NPSR1MEN1KMT2ASMN1; SMN2POLB
SCHEMBL9196329 0.70 NPSR1 (0.53) NPSR1MEN1KMT2ASMN1; SMN2POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1838 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260137082-A1 FUNGICIDAL COMPOSITIONS COMPRISING FLUDIOXONIL SYNGENTA CROP PROTECTION AG (CH) 2026-05-21 — — US claimed
US-20250017207-A1 FUNGICIDAL COMPOSITIONS SYNGENTA CROP PROTECTION AG (CH) 2025-01-16 — — US claimed
EP-4422402-A1 FUNGICIDAL COMPOSITIONS COMPRISING FLUDIOXONIL Syngenta Crop Protection AG (CH) 2024-09-04 — — EP claimed
EP-4422404-A1 FUNGICIDAL COMPOSITIONS Syngenta Crop Protection AG (CH) 2024-09-04 — — EP claimed
WO-2023072784-A1 FUNGICIDAL COMPOSITIONS COMPRISING FLUDIOXONIL SYNGENTA CROP PROTECTION AG (CH) 2023-05-04 — — WO claimed
WO-2023072785-A1 FUNGICIDAL COMPOSITIONS SYNGENTA CROP PROTECTION AG (CH) 2023-05-04 — — WO claimed
US-20230113346-A1 FUNGICIDAL COMPOSITIONS SYNGENTA CROP PROTECTION LLC (US) 2023-04-13 — — US claimed
WO-2020127319-A1 PLANT GROWTH REGULATOR COMPOSITIONS SYNGENTA CROP PROTECTION AG (CH) 2020-06-25 — — WO claimed
US-20150366201-A1 FUNGICIDAL COMPOSITIONS COMPRISING A CARBOXAMIDE SYNGENTA PARTICIPATIONS AG (CH) 2015-12-24 — — US claimed
US-20150181877-A1 FUNGICIDAL COMPOSITIONS SYNGENTA PARTICIPATIONS AG (CH) 2015-07-02 — — US claimed
US-20070244121-A1 Synergistic Fungicidal Compositions SYNGENTA CROP PROTECTION, INC. (US) 2007-10-18 — — US claimed
EP-1802198-A1 SYNERGISTIC FUNGICIDAL COMPOSITIONS Syngeta Participations AG (CH) 2007-07-04 — — EP claimed
EP-1796464-A1 FUNGICIDAL COMPOSITIONS Syngeta Participations AG (CH) 2007-06-20 — — EP claimed
EP-1778013-A1 FUNGICIDAL COMPOSITIONS Syngeta Participations AG (CH) 2007-05-02 — — EP claimed
WO-2007009661-A2 PESTICIDAL MIXTURES CONTAINING BICYCLIC ANTHRANILAMIDES SYNGENTA PARTICIPATIONS AG (CH) 2007-01-25 — — WO claimed
WO-2006037632-A1 SYNERGISTIC FUNGICIDAL COMPOSITIONS SYNGENTA PARTICIPATIONS AG (CH) 2006-04-13 — — WO claimed
WO-2006037633-A1 FUNGICIDAL COMPOSITIONS SYNGENTA PARTICIPATIONS AG (CH) 2006-04-13 — — WO claimed
WO-2006037634-A1 FUNGICIDAL COMPOSITIONS SYNGENTA PARTICIPATIONS AG (CH) 2006-04-13 — — WO claimed
WO-2006015865-A1 FUNGICIDAL COMPOSITIONS SYNGENTA PARTICIPATIONS AG (CH) 2006-02-16 — — WO claimed
EP-0449975-B1 NON-TIN-BASED, LOW TOXICITY ANTI-FOULING AGENTS BATTELLE MEMORIAL INSTITUTE (US) 1997-04-23 — — EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250017207-A1 FUNGICIDAL COMPOSITIONS CYP51A1, BROX, DPM1 NPSR1 4747/4885MEN1 3324/4885KMT2A 1352/4885
US-20150366201-A1 FUNGICIDAL COMPOSITIONS COMPRISING A CARBOXAMIDE CBR3, CBR1, C9 NPSR1 1704/4885MEN1 150/4885KMT2A 1512/4885
US-20260137082-A1 FUNGICIDAL COMPOSITIONS COMPRISING FLUDIOXONIL NOTUM, CTRL, BROX NPSR1 4167/4885MEN1 3442/4885KMT2A 1563/4885
US-20150181877-A1 FUNGICIDAL COMPOSITIONS CYP51A1, ERG28, DPM1 NPSR1 4746/4885MEN1 1353/4885KMT2A 2874/4885
US-20070244121-A1 Synergistic Fungicidal Compositions DDT, CRY1, HCN1 NPSR1 4031/4885MEN1 337/4885KMT2A 2009/4885
US-20230113346-A1 FUNGICIDAL COMPOSITIONS BROX, RER1, BLVRB NPSR1 4592/4885MEN1 749/4885KMT2A 1389/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.