SCHEMBL433769

SCHEMBL433769

CC(C)(C)OC(=O)NCc1ccc(B(O)O)cc1

nearest known ligand 0.53

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TRPV1 Q8NER1 7/20 0.53
L3MBTL1 Q9Y468 2/20 0.52
NAMPT P43490 2/20 0.50
GAA P10253 1/20 0.50
CA1 P00915 1/20 0.47
CA2 P00918 1/20 0.47
HDAC1 Q13547 2/20 0.46
MAPT P10636 2/20 0.44
TDP1 Q9NUW8 1/20 0.44
RECQL P46063 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3180689 0.88 L3MBTL1 (0.61) L3MBTL1NAMPTGAACA1CA2
SCHEMBL20019864 0.85 CA1 (0.49) TRPV1L3MBTL1GAACA1CA2
SCHEMBL1585947 0.85 CA2 (0.53) TRPV1NAMPTCA1CA2MAPT
SCHEMBL6609140 0.83 TSHR (0.56) TRPV1
Boric Acid SCHEMBL27878882 0.83 HPGD (0.55) L3MBTL1NAMPTGAACA1CA2
SCHEMBL3519181 0.83 HDAC1 (0.56) TRPV1L3MBTL1NAMPTGAAHDAC1
SCHEMBL1162968 0.82 GLS (0.49) L3MBTL1NAMPTCA1HDAC1
SCHEMBL1164796 0.82 L3MBTL1 (0.56) L3MBTL1NAMPTGAACA1CA2
SCHEMBL5796279 0.82 L3MBTL1 (0.56) L3MBTL1NAMPTGAACA1CA2
SCHEMBL15259134 0.82 L3MBTL1 (0.56) L3MBTL1NAMPTGAACA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 534 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112707924-A Synthetic method of 4-aminomethyl phenylboronic acid hydrochloride 蚌埠中实化学技术有限公司 2021-04-27 CN claimed
US-9938410-B2 Rhodamine dyes and conjugates PHARMACOPHOTONICS, INC. (US) 2018-04-10 US claimed
US-20160208101-A1 NOVEL RHODAMINE DYES AND CONJUGATES PHARMACOPHOTONICS, INC. D/B/A FAST DIAGNOSTICS 2016-07-21 US claimed
EP-3802500-B1 MELANOCORTIN SUBTYPE-2 RECEPTOR (MC2R) ANTAGONISTS AND USES THEREOF CRINETICS PHARMACEUTICALS INC (US) 2026-05-27 EP disclosed
US-12590062-B2 PD-1/PD-L1 inhibitors GILEAD SCIENCES, INC. (US) 2026-03-31 US disclosed
US-12552801-B2 Indazole derivatives HOFFMANN-LA ROCHE INC. (US) 2026-02-17 US disclosed
US-20260042762-A1 MERTK DEGRADERS AND USES THEREOF KYMERA THERAPEUTICS INC (US) 2026-02-12 US disclosed
US-12479828-B2 Melanocortin subtype-2 receptor (MC2R) antagonists and uses thereof Crinetics Pharmaceuticals, Inc. (US) 2025-11-25 US disclosed
EP-4650001-A2 FUSED HETEROCYCLIC DERIVATIVES AS NEGATIVE ALLOSTERIC MODULATORS OF MGLU7 RECEPTOR Neurosterix Pharma Sàrl (CH) 2025-11-19 EP disclosed
US-12466805-B2 Pharmaceutical compounds ALMAC DISCOVERY LIMITED (GB) 2025-11-11 US disclosed
EP-4337664-B1 FUSED HETEROCYCLIC DERIVATIVES AS NEGATIVE ALLOSTERIC MODULATORS OF MGLU7 RECEPTOR ADDEX PHARMACEUTICALS SA (CH) 2025-10-01 EP disclosed
EP-1720836-A1 6-SUBSTITUTED 2,3,4,5-TETRAHYDRO-1H-BENZO [D]AZEPINES AS 5-HT2C RECEPTOR AGONISTS ELI LILLY AND COMPANY (US) 2006-11-15 EP disclosed
US-20060178366-A1 Compounds for the treatment of inflammatory disorders SCHERING CORPORATION 2006-08-10 US disclosed
US-20060178366-A1 Compounds for the treatment of inflammatory disorders SCHERING CORPORATION 2006-08-10 US disclosed
US-20060128741-A1 8H-imidazo[4,5-D]thiazolo[4,5-B]pyridine based tricyclic compounds and pharmaceutical compositions comprising same BRISTOL-MYERS SQUIBB COMPANY 2006-06-15 US disclosed
US-20060106062-A1 Substituted 2-quinolyl-oxazoles useful as PDE4 inhibitors SCHERING CORPORATION 2006-05-18 US disclosed
WO-2006053166-A1 8H-IMIDAZO[4,5-D]THIAZOLO[4,5-B]PYRIDINE BASED TRICYCLIC COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS COMPRISING SAME BRISTOL-MYERS SQUIBB COMPANY (US) 2006-05-18 WO disclosed
WO-2005121130-A2 CHEMICAL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM FOR THE TREATMENT OF INFLAMMATORY DISORDERS SCHERING CORPORATION (US) 2005-12-22 WO disclosed
WO-2005116009-A1 SUBSTITUTED 2-QUINOLYL-OXAZOLES USEFUL AS PDE4 INHIBITORS SCHERING CORPORATION (US) 2005-12-08 WO disclosed
WO-2005082859-A1 6-SUBSTITUTED 2,3,4,5-TETRAHYDRO-1H-BENZO[D]AZEPINES AS 5-HT2C RECEPTOR AGONISTS ELI LILLY AND COMPANY (US) 2005-09-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12466805-B2 Pharmaceutical compounds USP19, USP18, UBE2I TRPV1 4569/4885L3MBTL1 4680/4885NAMPT 2821/4885
US-20060178366-A1 Compounds for the treatment of inflammatory disorders MMP12, ADAMTS1, TNF TRPV1 1158/4885L3MBTL1 4829/4885NAMPT 451/4885
US-20260042762-A1 MERTK DEGRADERS AND USES THEREOF MERTK, CRKL, OSTC TRPV1 3927/4885L3MBTL1 3922/4885NAMPT 235/4885
US-20060106062-A1 Substituted 2-quinolyl-oxazoles useful as PDE4 inhibitors PDE4A, PDE4B, PDE3B TRPV1 4447/4885L3MBTL1 4260/4885NAMPT 4357/4885
US-12590062-B2 PD-1/PD-L1 inhibitors CD274, PDCD1LG2, PDCD1 TRPV1 4586/4885L3MBTL1 1047/4885NAMPT 2881/4885
US-12479828-B2 Melanocortin subtype-2 receptor (MC2R) antagonists and uses thereof MC3R, MC1R, MC2R TRPV1 155/4885L3MBTL1 4237/4885NAMPT 446/4885
US-12552801-B2 Indazole derivatives EGFR, ABL1, ERBB3 TRPV1 911/4885L3MBTL1 2446/4885NAMPT 3420/4885
US-20060128741-A1 8H-imidazo[4,5-D]thiazolo[4,5-B]pyridine based tricyclic compounds and pharmaceutical compositions comprising same IL4, IL5, CYP4B1 TRPV1 126/4885L3MBTL1 4047/4885NAMPT 1130/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.