Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | ACHE | P22303 | 2/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 9/20 | 0.35 |
| ▸ | MPEG1 | Q2M385 | 7/20 | 0.35 |
| ▸ | XIAP | P98170 | 2/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | PTGES | O14684 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1194296 | 0.98 | KCNH2 (0.35) | KCNH2ACHEBACE1ALOX5MPEG1 | |
| SCHEMBL17419219 | 0.90 | KCNH2 (0.33) | KCNH2ACHEBACE1ALOX5MPEG1 | |
| SCHEMBL6004328 | 0.88 | ALOX5 (0.33) | KCNH2ALOX5MPEG1XIAPGPR84 | |
| SCHEMBL6003914 | 0.81 | ALOX5 (0.31) | ACHEBACE1ALOX5MPEG1XIAP | |
| SCHEMBL5011897 | 0.80 | KCNH2 (0.36) | KCNH2GPR84 | |
| SCHEMBL17681578 | 0.79 | CASP3 (0.42) | ALDH1A1PTGESMAPTHPGD | |
| SCHEMBL1772836 | 0.79 | ALOX5 (0.30) | ALOX5MPEG1XIAPGPR84KDM4E | |
| SCHEMBL2337738 | 0.77 | GCGR (0.40) | KCNH2ACHEALOX5KDM4EALDH1A1 | |
| SCHEMBL5601662 | 0.63 | THRB (0.40) | KCNH2ALOX5MPEG1XIAPGPR84 | |
| SCHEMBL31054446 | 0.58 | KCNH2 (0.50) | KCNH2ACHEGPR84KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3459955-B1 | NOVEL METHOD AND APPLICATION OF UNSYMMETRICALLY MESO-SUBSTITUTED PORPHYRINS AND CHLORINS FOR PDT | BIOLITEC UNTERNEHMENSBERATUNGS II AG (AT) | 2022-11-02 | — | — | EP | disclosed |
| EP-3459955-A1 | NOVEL METHOD AND APPLICATION OF UNSYMMETRICALLY MESO-SUBSTITUTED PORPHYRINS AND CHLORINS FOR PDT | biolitec Unternehmensbeteiligungs II AG (AT) | 2019-03-27 | — | — | EP | disclosed |
| EP-2350058-B1 | NOVEL METHOD AND APPLICATION OF UNSYMMETRICALLY MESO-SUBSTITUTED PORPHYRINS AND CHLORINS FOR PDT | BIOLITEC UNTERNEHMENSBETEILIGUNGS II AG (AT) | 2018-10-24 | — | — | EP | disclosed |
| EP-2870159-B1 | APPLICATION OF ß-FUNCTIONALIZED DIHYDROXY-CHLORINS FOR PDT | BIOLITEC UNTERNEHMENSBETEILIGUNGS II AG (AT) | 2017-06-28 | — | — | EP | disclosed |
| US-9315510-B2 | Method and application of unsymmetrically meso-substituted porphyrins and chlorins for PDT | BIOLITEC PHARMA MARKETING LTD (MY) | 2016-04-19 | — | — | US | disclosed |
| US-9156849-B2 | Application of β-functionalized dihydroxy-chlorins for PDT | BIOLITEC PHARMA MARKETING LTD (MY) | 2015-10-13 | — | — | US | disclosed |
| EP-2870159-A2 | APPLICATION OF ß-FUNCTIONALIZED DIHYDROXY-CHLORINS FOR PDT | CeramOptec GmbH (DE) | 2015-05-13 | — | — | EP | disclosed |
| US-20130041307-A1 | APPLICATION OF BETA-FUNCTIONALIZED DIHYDROXY-CHLORINS FOR PDT | CERAMOPTEC INDUSTRIES, INC. | 2013-02-14 | — | — | US | disclosed |
| WO-2012012809-A2 | APPLICATION OF β-FUNCTIONALIZED DIHYDROXY-CHLORINS FOR PDT | CERAMOPTEC GMBH (DE) | 2012-01-26 | — | — | WO | disclosed |
| US-20110206613-A1 | METHOD AND APPLICATION OF UNSYMMETRICALLY meso-SUBSTITUTED PORPHYRINS AND CHLORINS FOR PDT | BIOLITEC UNTERNEHMENSBETEILIGUNGS II AG (AT) | 2011-08-25 | — | — | US | disclosed |
| EP-2350058-A2 | NOVEL METHOD AND APPLICATION OF UNSYMMETRICALLY MESO-SUBSTITUTED PORPHYRINS AND CHLORINS FOR PDT | CeramOptec GmbH (DE) | 2011-08-03 | — | — | EP | disclosed |
| WO-2010033678-A2 | NOVEL METHOD AND APPLICATION OF UNSYMMETRICALLY MESO-SUBSTITUTED PORPHYRINS AND CHLORINS FOR PDT | CERAMOPTEC INDUSTRIES, INC. (US) | 2010-03-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110206613-A1 | METHOD AND APPLICATION OF UNSYMMETRICALLY meso-SUBSTITUTED PORPHYRINS AND CHLORINS FOR PDT | PTDSS2, PTDSS1, DLST | KCNH2 1786/4885ACHE 3323/4885BACE1 4437/4885 |
| US-20130041307-A1 | APPLICATION OF BETA-FUNCTIONALIZED DIHYDROXY-CHLORINS FOR PDT | TK1, DHPS, DLD | KCNH2 1082/4885ACHE 4203/4885BACE1 3414/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.