SCHEMBL9602115

SCHEMBL9602115

O=C(Cl)c1ccc(Cc2ccc3c(c2)C(=O)OC3=O)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 5/20 0.39
CA7 P43166 5/20 0.39
CA1 P00915 4/20 0.39
CA2 P00918 2/20 0.39
CA9 Q16790 1/20 0.39
CA4 P22748 2/20 0.39
KMT2A Q03164 2/20 0.38
PLA2G2A P14555 2/20 0.38
PLA2G10 O15496 1/20 0.38
LMNA P02545 1/20 0.38
ALDH1A1 P00352 1/20 0.36
HAO1 Q9UJM8 1/20 0.35
ALOX15 P16050 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
SRD5A2 P31213 1/20 0.34
HNF4A P41235 1/20 0.34
HDAC1 Q13547 1/20 0.34
HDAC6 Q9UBN7 1/20 0.34
MAPT P10636 1/20 0.34
MCL1 Q07820 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL434869 0.83 ALOX15 (0.50) CA12CA7CA1CA2CA4
SCHEMBL74379 0.81 CA12 (0.49) CA12CA7CA1CA2CA9
SCHEMBL29490657 0.81 CA12 (0.49) CA12CA7CA1CA2CA9
SCHEMBL889584 0.80 ALOX15 (0.48) PLA2G2APLA2G10LMNAALDH1A1ALOX15
SCHEMBL23630427 0.79 CA12 (0.42) CA12CA7CA1CA2CA9
SCHEMBL9602971 0.79 CA12 (0.45) CA12CA7CA1CA2CA9
SCHEMBL29868120 0.79 CA12 (0.42) CA12CA7CA1CA2CA9
SCHEMBL1290930 0.77 KMT2A (0.58) CA12CA1CA2CA9KMT2A
SCHEMBL19927918 0.77 ALDH1A1 (0.40) CA12CA7CA1CA4KMT2A
SCHEMBL9601824 0.75 MAOA (0.44) CA12CA7CA1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0315992-B1 SULFUR-CONTAINING AROMATIC TETRACARBOXYLIC ACIDS AND THEIR DERIVATIVES CHEMIE LINZ GMBH (AT) 1993-08-11 EP disclosed
US-5126462-A Monomers for soluble, fusible polyimides or polyamideimides CHEMIE LINZ GESELLSCHAFT M.B.H. (AT) 1992-06-30 US disclosed
EP-0315993-B1 SOLUBLE AND/OR FUSIBLE BLOCK POLYAMIDE-POLYAMIDES, POLYAMIDE-POLYAMIDEIMIDES AND POLYAMIDES-POLYIMIDES Chemie Linz Gesellschaft m.b.H. (AT) 1992-04-01 EP disclosed
EP-0390803-A1 SULFUR-CONTAINING AROMATIC TETRACARBOXYLIC ACIDS AND THEIR DERIVATIVES Chemie Linz Gesellschaft m.b.H. (AT) 1990-10-10 EP disclosed
WO-1989004298-A1 SULFUR-CONTAINING AROMATIC TETRACARBOXYLIC ACIDS AND THEIR DERIVATIVES CHEMIE LINZ GESELLSCHAFT M.B.H. (AT) 1989-05-18 WO disclosed
EP-0315992-A1 Sulfur-containing aromatic tetracarboxylic acids and their derivatives Chemie Linz Gesellschaft m.b.H. (AT) 1989-05-17 EP disclosed
EP-0315993-A1 Soluble and/or fusible block polyamide-polyamides, polyamide-polyamideimides and polyamides-polyimides Chemie Linz Gesellschaft m.b.H. (AT) 1989-05-17 EP disclosed