Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Menadione Sulfurous Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 known ✓ | P00915 | 3/20 | 0.34 |
| ▸ | CA2 known ✓ | P00918 | 3/20 | 0.34 |
| ▸ | CA4 known ✓ | P22748 | 2/20 | 0.33 |
| ▸ | THRB known ✓ | P10828 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.97 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.97 |
| ▸ | POLB | P06746 | 2/20 | 0.97 |
| ▸ | PARG | Q86W56 | 1/20 | 0.37 |
| ▸ | PKLR | P30613 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | RECQL | P46063 | 2/20 | 0.34 |
| ▸ | CA9 | Q16790 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Menadione Sulfurous Acid SCHEMBL29973176 | 1.00 | MEN1 (0.97) | MEN1KMT2APOLBPARGPKLR | |
| Menadione Sulfurous Acid SCHEMBL461612 | 0.98 | MEN1 (1.00) | MEN1KMT2APOLBPARGPKLR | |
| Menadione Sulfurous Acid SCHEMBL29364956 | 0.98 | MEN1 (1.00) | MEN1KMT2APOLBPARGPKLR | |
| Menadione Sulfurous Acid SCHEMBL460403 | 0.98 | MEN1 (1.00) | MEN1KMT2APOLBPARGPKLR | |
| Menadione Sulfurous Acid SCHEMBL459906 | 0.97 | MEN1 (0.91) | MEN1KMT2APOLBPARGPKLR | |
| Menadione Sulfurous Acid SCHEMBL461201 | 0.97 | MEN1 (0.91) | MEN1KMT2APOLBPARGPKLR | |
| SCHEMBL18309831 | 0.83 | MEN1 (0.69) | MEN1KMT2APOLBPARGALDH1A1 | |
| Menadione Sulfurous Acid SCHEMBL18314150 | 0.81 | POLB (0.67) | MEN1KMT2APOLBPARGALDH1A1 | |
| Menadione Sulfurous Acid SCHEMBL459525 | 0.81 | POLB (0.67) | MEN1KMT2APOLBPARGALDH1A1 | |
| Menadione Sulfurous Acid SCHEMBL459627 | 0.80 | POLB (0.65) | MEN1KMT2APOLBPARGALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2090 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3794005-B1 | INORGANIC SALTS OF NICOTINIC ACID MONONUCLEOTIDE AS ANTI-AGING AGENTS | Jumpstart Fertility Pty Ltd (AU) | 2025-10-22 | — | — | EP | claimed |
| US-20250243606-A1 | ANTIBACTERIAL AND ANTIVIRAL FABRICS | UNIV CALIFORNIA (US) | 2025-07-31 | — | — | US | claimed |
| US-12295957-B2 | Ascorbic acid and quinone compounds in combination with an antiparasitic agent for treating a parasitic disease | IC-MedTech Corp. (US) | 2025-05-13 | — | — | US | claimed |
| CN-119791112-A | Application of naphthoquinone compound in preparation of nematode prevention and control medicament | 贵州大学 | 2025-04-11 | — | — | CN | claimed |
| US-12270127-B2 | Antibacterial and antiviral fabrics | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2025-04-08 | — | — | US | claimed |
| US-20250111893-A1 | SYSTEMS AND METHODS FOR CUSTOMIZING CELL CULTURE MEDIA FOR OPTIMIZED CELL PROLIFERATION BASED ON GENETIC TRAITS OF CELLS | WONDERLAB HOLDINGS, INC. | 2025-04-03 | — | — | US | claimed |
| US-12264162-B2 | Cotton fabrics containing porous organic cages | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2025-04-01 | — | — | US | claimed |
| US-20240398755-A1 | ASCORBIC ACID AND QUINONE COMPOUNDS FOR TREATING CHAGAS DISEASE | IC-MedTech Corp. | 2024-12-05 | — | — | US | claimed |
| CN-118831075-A | Compound medicine for delaying skeletal muscle aging and application thereof | 中国医科大学 | 2024-10-25 | — | — | CN | claimed |
| US-12087399-B2 | Systems and methods for customizing cell culture media for optimized cell proliferation based on genetic traits of cells | SAPPHIROS AI BIO LLC (US) | 2024-09-10 | — | — | US | claimed |
| WO-2002055530-A2 | TRANSCOBALAMIN BINDING CONJUGATES USEFUL FOR TREATING ABNORMAL CELLULAR PROLIFERATION | MAYO FOUNDATION (US) | 2002-07-18 | — | — | WO | claimed |
| US-6156355-A | Breed-specific canine food formulations | STAR-KIST FOODS, INC. (US) | 2000-12-05 | — | — | US | claimed |
| US-5635198-A | ACTIVE SUBSTANCE CONTAINING FIRST COATING OF FATTY ACID OR ESTER, OR ANIMAL OR VEGETABLE FAT OR OIL, AND A WAX AND SECOND COATING OF TABULAR CRYSTALS THAT ARE SPARINGLY WATER-SOLUBLE BUT READILY SOLUBLE IN ACIDIC MEDIUM | SHOWA DENKO K.K. (JP) | 1997-06-03 | — | — | US | claimed |
| US-5633004-A | MULTILAYERED, FIRST LAYER SELECTED FROM FATTY ACID OR ANIMAL OR VEGETABLE OIL, AND A WAX, SECOND TUBULAR CRYSTAL LAYER, WATER SOLUBLE ONLY UNDER ACIDIC CONDITION CONSISTS OF AN AMINO ACID AND CALCIUM HYDROGEN PHSPHATE DIHYDRATE; FEEDS | SHOWA DENKO K.K. (JP) | 1997-05-27 | — | — | US | claimed |
| US-5571527-A | CORE WITH A COATING OF LAMINAR TABULAR CRYSTALS, ABSORPTION IN THE ABOMASUM, AMINO ACIDS | SHOWA DENKO K. K. (JP) | 1996-11-05 | — | — | US | claimed |
| US-5128151-A | STABILIZED MENADIONE BISULFITE FORMULATIONS AND THEIR PREPARATION | BASF AKTIENGESELLSCHAFT (DE) | 1992-07-07 | — | — | US | claimed |
| EP-0275880-B1 | PROCESS FOR PRODUCING STABILIZED MENADION BISULFIDE FORMULATIONS | BASF Aktiengesellschaft (DE) | 1991-07-24 | — | — | EP | claimed |
| EP-0234940-B1 | NOVEL DERIVATIVES BASED UPON PYRIDO-MENADIONE ADDUCTS AND USES THEREOF | Heterochemical Corporation (US) | 1991-04-17 | — | — | EP | claimed |
| US-4764201-A | Plant growth regulation | TOMOE KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1988-08-16 | — | — | US | claimed |
| EP-0234940-A2 | Novel derivatives based upon pyrido-menadione adducts and uses thereof | Heterochemical Corporation (US) | 1987-09-02 | — | — | EP | claimed |