Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ST14 | Q9Y5Y6 | 4/20 | 0.39 |
| ▸ | F2 | P00734 | 3/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.39 |
| ▸ | F10 | P00742 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.35 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.35 |
| ▸ | TAS2R14 | Q9NYV8 | 2/20 | 0.34 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.34 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.34 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.34 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.34 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.34 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | PLG | P00747 | 1/20 | 0.33 |
| ▸ | MMP1 | P03956 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4370550 | 0.84 | HDAC6 (0.37) | ST14F2PRSS1PRSS2PRSS3 | |
| SCHEMBL1797575 | 0.78 | MMP2 (0.43) | ST14F2PRSS1PRSS2PRSS3 | |
| SCHEMBL4377255 | 0.75 | MEP1B (0.36) | ST14F2PRSS1PRSS2PRSS3 | |
| SCHEMBL4373478 | 0.73 | F2 (0.48) | ST14F2PRSS1PRSS2PRSS3 | |
| SCHEMBL1802359 | 0.68 | MMP2 (0.43) | ST14F2F10PLGMMP1 | |
| SCHEMBL4372258 | 0.66 | F2 (0.41) | ST14F2PRSS1PRSS2PRSS3 | |
| SCHEMBL4372182 | 0.66 | F10 (0.51) | ST14F2F10PLG | |
| SCHEMBL1799336 | 0.66 | F2 (0.34) | ST14F2PRSS1PRSS2PRSS3 | |
| SCHEMBL328409 | 0.65 | MMP1 (0.38) | TAS2R14MMP1MMP13 | |
| SCHEMBL6852278 | 0.64 | CACNA1H (0.40) | TAS2R14MMP1MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1461313-B1 | HUMAN ADAM-10 INHIBITORS | EXELIXIS INC (US) | 2009-08-05 | — | — | EP | disclosed |