Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.45 |
| ▸ | NOS3 | P29474 | 1/20 | 0.40 |
| ▸ | NOS2 | P35228 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | FEN1 | P39748 | 4/20 | 0.39 |
| ▸ | ALOX5AP | P20292 | 3/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | NCF1 | P14598 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 2/20 | 0.38 |
| ▸ | ILK | Q13418 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | SCN4A | P35499 | 1/20 | 0.37 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.37 |
| ▸ | MET | P08581 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL436530 | 0.87 | BACE1 (0.42) | MAOBNOS3NOS2BACE1FEN1 | |
| SCHEMBL438632 | 0.81 | PARP1 (0.45) | MAOBPARP1NOS3NOS2BACE1 | |
| SCHEMBL1346304 | 0.81 | MAOB (0.46) | MAOBPARP1ADRB2NCF1KIF11 | |
| SCHEMBL9591539 | 0.81 | MAOB (0.46) | MAOBPARP1ADRB2NCF1KIF11 | |
| SCHEMBL439004 | 0.78 | ACHE (0.43) | BACE1 | |
| SCHEMBL437952 | 0.78 | ACHE (0.45) | BACE1 | |
| SCHEMBL439912 | 0.77 | ALOX5AP (0.42) | FEN1ALOX5APKIF11SCN4A | |
| SCHEMBL438818 | 0.76 | ALDH1A1 (0.53) | PARP1FEN1ALOX5AP | |
| SCHEMBL437293 | 0.75 | ACHE (0.43) | PARP1NOS3NOS2 | |
| SCHEMBL9829215 | 0.75 | ADRB2 (0.51) | MAOBPARP1NOS3NOS2ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065166-A1 | Bone Modulators And Methods Therewith | ESPINA VIRGINIA (US) | 2012-03-15 | — | — | US | disclosed |