Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.43 |
| ▸ | FERMT2 | Q96AC1 | 1/20 | 0.39 |
| ▸ | GRM5 | P41594 | 6/20 | 0.38 |
| ▸ | TDO2 | P48775 | 1/20 | 0.35 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.35 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.35 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.34 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL439853 | 0.86 | BCHE (0.43) | ACHEMAP4K4BACE1 | |
| SCHEMBL437952 | 0.81 | ACHE (0.45) | ACHEBACE1 | |
| SCHEMBL9377343 | 0.81 | ACHE (0.45) | ACHEFERMT2GRM5TDO2BACE1 | |
| SCHEMBL437293 | 0.79 | ACHE (0.43) | ACHE | |
| SCHEMBL438239 | 0.79 | ACHE (0.46) | ACHEFERMT2GRM5 | |
| SCHEMBL437067 | 0.78 | MAOB (0.46) | BACE1 | |
| SCHEMBL437945 | 0.75 | ACHE (0.47) | ACHEFERMT2PDGFRBPDGFRA | |
| SCHEMBL439912 | 0.74 | ALOX5AP (0.42) | — | |
| SCHEMBL438745 | 0.73 | KEAP1 (0.49) | ACHEMAP4K4 | |
| SCHEMBL439796 | 0.73 | KDM4E (0.50) | ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065166-A1 | Bone Modulators And Methods Therewith | ESPINA VIRGINIA (US) | 2012-03-15 | — | — | US | disclosed |