Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.43 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.43 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.43 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.43 |
| ▸ | LIPE | Q05469 | 4/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4371434 | 0.86 | SRD5A2 (0.49) | GRM4LMNARAB9AMEN1NPC1 | |
| SCHEMBL4371705 | 0.85 | MAOB (0.54) | GRM4LMNARAB9AMEN1NPC1 | |
| SCHEMBL4374065 | 0.76 | THRB (0.47) | LMNARAB9AMAPTMAOB | |
| SCHEMBL11097560 | 0.72 | MEN1 (0.45) | LMNARAB9AMEN1NPC1ALDH1A1 | |
| SCHEMBL68177 | 0.72 | CES2 (0.67) | MEN1HPGDKMT2AKCNQ3KCNQ2 | |
| SCHEMBL4370646 | 0.72 | KIF11 (0.47) | GRM4MAPTMAOB | |
| SCHEMBL4371648 | 0.72 | MAOB (0.54) | LMNAALDH1A1MAPTMAOB | |
| SCHEMBL7090499 | 0.72 | LMNA (0.65) | LMNARAB9ANPC1MAPTLIPE | |
| SCHEMBL21628911 | 0.71 | LMNA (0.64) | LMNARAB9AMAPTLIPEMAOB | |
| SCHEMBL21628386 | 0.71 | LMNA (0.63) | LMNAALDH1A1HPGDLIPE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009117421-A2 | HETEROCYCLIC MODULATORS OF GPR119 FOR TREATMENT OF DISEASE | KALYPSYS, INC. (US) | 2009-09-24 | — | — | WO | disclosed |