SCHEMBL4373395

SCHEMBL4373395

C=CC(=O)C(O)C(O)CO

nearest known ligand 0.39

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
PDE4A P27815 1/20 0.39
LMNA P02545 3/20 0.37
L3MBTL1 Q9Y468 1/20 0.35
TDP1 Q9NUW8 1/20 0.33
USP2 O75604 1/20 0.32
SLCO1B1 Q9Y6L6 1/20 0.32
OR51E2 Q9H255 1/20 0.31
AKR1B1 P15121 1/20 0.31
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8323167 0.86 PDE4A (0.46) PDE4ALMNAL3MBTL1TDP1USP2
SCHEMBL27810471 0.84 PDE4A (0.56) PDE4ALMNAL3MBTL1TDP1USP2
SCHEMBL18452554 0.84 PDE4A (0.56) PDE4ALMNAL3MBTL1TDP1USP2
SCHEMBL28066560 0.78 TSHR (0.39) TSHR
SCHEMBL9747332 0.78 LMNA (0.41) LMNATDP1TSHR
SCHEMBL471726 0.77 PDE4A (0.41) PDE4ALMNAL3MBTL1TDP1USP2
SCHEMBL1478552 0.77 PDE4A (0.41) PDE4ALMNAL3MBTL1TDP1USP2
SCHEMBL29720316 0.77 PDE4A (0.41) PDE4ALMNAL3MBTL1TDP1USP2
SCHEMBL817588 0.77 PDE4A (0.41) PDE4ALMNAL3MBTL1TDP1USP2
SCHEMBL2783948 0.76 ALDH1A1 (0.37) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009129221-A1 POLYFUNCTIONAL COMPOUNDS AND GLASS-IONOMER CEMENT COMPOSITIONS AND METHODS FOR USING AS IMPLANT MATERIALS INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) 2009-10-22 WO claimed
JP-8119846-A None JP disclosed
US-20240156853-A1 IN VITRO AND IN VIVO INTRACELLULAR DELIVERY OF SIRNA VIA SELF-ASSEMBLED NANOPIECES RHODE ISLAND HOSPITAL 2024-05-16 US disclosed
CN-117204119-A Thin film heater and glass with heater TDK株式会社 2023-12-08 CN disclosed
CN-117178630-A Thin film heater and glass with heater TDK株式会社 2023-12-05 CN disclosed
US-11701379-B2 In vitro and in vivo intracellular delivery of siRNA via self-assembled nanopieces RHODE ISLAND HOSPITAL (US) 2023-07-18 US disclosed
US-20210023117-A1 IN VITRO AND IN VIVO INTRACELLULAR DELIVERY OF SIRNA VIA SELF-ASSEMBLED NANOPIECES NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2021-01-28 US disclosed
US-20200375991-A1 NANOCARRIERS AND THEIR PROCESSING FOR DIAGNOSTICS AND THERAPEUTICS RHODE ISLAND HOSPITAL 2020-12-03 US disclosed
CN-107735468-B Method for preparing organopolysiloxanes comprising (meth) acrylate functions 蓝星有机硅法国两合公司 2020-10-27 CN disclosed
US-10555948-B2 Nanocarriers and their processing for diagnostics and therapeutics RHODE ISLAND HOSPITAL (US) 2020-02-11 US disclosed
CN-105451746-A Compositions comprising crosslinked cationically binding polymers RELYPSA INC 2016-03-30 CN disclosed
US-20150258094-A1 Nanocarriers And Their Processing For Diagnostics And Therapeutics RHODE ISLAND HOSPITAL 2015-09-17 US disclosed
WO-2015139051-A2 NANOCARRIERS AND THEIR PROCESSING FOR DIAGNOSTICS AND THERAPEUTICS RHODE ISLAND HOSPITAL (US) 2015-09-17 WO disclosed
CN-1068182-C Non-stick chewing gum WARNER LAMBERT CO (US) 2001-07-11 CN disclosed
CN-1207501-A Lenses obtained from high-speed polymerizable resin composition MITSUI CHEMICALS INC (JP) 1999-02-10 CN disclosed
CN-1040651-C High-speed polymerizable resin composition and lens made of the same MITSUI TOATSU CHEMICALS (JP) 1998-11-11 CN disclosed
CN-1171726-A Non-stick chewing gum WARNER LAMBERT CO (US) 1998-01-28 CN disclosed
JP-H08119846-A PROTECTING AGENT FOR SKIN SUZUKI YUSHI KOGYO KK 1996-05-14 JP disclosed
CN-1106841-A High-speed polymerizable resin composition and lens made of the same MITSUI TOATSU CHEMICALS (JP) 1995-08-16 CN disclosed
EP-0097864-A1 Photopolymerizable mixture and photopolymerizable copying material produced therewith HOECHST AKTIENGESELLSCHAFT (DE) 1984-01-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150258094-A1 Nanocarriers And Their Processing For Diagnostics And Therapeutics SYVN1, SSB, TNF PDE4A 2797/4885LMNA 379/4885L3MBTL1 2881/4885
US-11701379-B2 In vitro and in vivo intracellular delivery of siRNA via self-assembled nanopieces NFATC1, TRAF6, UACA PDE4A 2671/4885LMNA 415/4885L3MBTL1 693/4885
US-20210023117-A1 IN VITRO AND IN VIVO INTRACELLULAR DELIVERY OF SIRNA VIA SELF-ASSEMBLED NANOPIECES NFATC1, TRAF6, UACA PDE4A 2671/4885LMNA 415/4885L3MBTL1 693/4885
US-10555948-B2 Nanocarriers and their processing for diagnostics and therapeutics SYVN1, SSB, TNF PDE4A 2797/4885LMNA 379/4885L3MBTL1 2881/4885
US-20200375991-A1 NANOCARRIERS AND THEIR PROCESSING FOR DIAGNOSTICS AND THERAPEUTICS SYVN1, SSB, TNF PDE4A 2797/4885LMNA 379/4885L3MBTL1 2881/4885
US-20240156853-A1 IN VITRO AND IN VIVO INTRACELLULAR DELIVERY OF SIRNA VIA SELF-ASSEMBLED NANOPIECES NFATC1, TRAF6, UACA PDE4A 2671/4885LMNA 415/4885L3MBTL1 693/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.