Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.38 |
| ▸ | HTR2C | P28335 | 2/20 | 0.38 |
| ▸ | HTR2B | P41595 | 2/20 | 0.38 |
| ▸ | ADCY10 | Q96PN6 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.37 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
| ▸ | OXTR | P30559 | 1/20 | 0.36 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.36 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4380448 | 0.92 | LTA4H (0.43) | HTR2AHTR2CHTR2BDRD2 | |
| SCHEMBL4384328 | 0.87 | PTPN1 (0.36) | HTR2AHTR2CHTR2BPTPN1DRD2 | |
| SCHEMBL4381198 | 0.87 | PTPN1 (0.38) | HTR2AHTR2CHTR2BPTPN1KDM4E | |
| SCHEMBL4384579 | 0.85 | PTPN1 (0.37) | HTR2AHTR2CHTR2BPTPN1 | |
| SCHEMBL4381287 | 0.85 | CTSS (0.36) | PTPN1KDM4EDRD2 | |
| SCHEMBL4374731 | 0.83 | PTPN1 (0.54) | HTR2BCNR2PTPN1PIK3CDPIK3CA | |
| SCHEMBL4378503 | 0.82 | PTPN1 (0.48) | HTR2AHTR2CHTR2BPTPN1 | |
| SCHEMBL3742273 | 0.81 | PTPN1 (0.36) | HTR2AHTR2CHTR2BPTPN1 | |
| SCHEMBL4379622 | 0.80 | PTPN1 (0.37) | HTR2AHTR2CHTR2BPTPN1 | |
| SCHEMBL4389955 | 0.79 | PTPN1 (0.51) | HTR2AHTR2CHTR2BPTPN1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1910359-B1 | PYRIDO [2 , 3-D]PYRIMIDINE-2 , 4-DIAMINE COMPOUNDS AS PTPlB INHIBITORS | HOFFMANN LA ROCHE (CH) | 2009-11-18 | — | — | EP | claimed |