Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 5/20 | 0.39 |
| ▸ | DPP7 | Q9UHL4 | 5/20 | 0.39 |
| ▸ | DPP9 | Q86TI2 | 4/20 | 0.39 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.39 |
| ▸ | FAP | Q12884 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 4/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.35 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.34 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.34 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.34 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.34 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4372598 | 0.83 | NR3C1 (0.48) | DPP4DPP7DPP9DPP8FAP | |
| SCHEMBL4377255 | 0.82 | MEP1B (0.36) | MMP13 | |
| SCHEMBL4370550 | 0.77 | HDAC6 (0.37) | MMP13 | |
| SCHEMBL4382974 | 0.73 | NR3C1 (0.53) | ALOX5MMP13 | |
| SCHEMBL1799336 | 0.71 | F2 (0.34) | — | |
| SCHEMBL4372334 | 0.68 | LTA4H (0.40) | ALOX5ADAMTS4MMP13 | |
| SCHEMBL4372629 | 0.67 | PKM (0.41) | DPP4SCN9AMMP13 | |
| SCHEMBL2804528 | 0.67 | DPP7 (0.43) | DPP4DPP7DPP9DPP8FAP | |
| SCHEMBL4293042 | 0.66 | LTA4H (0.33) | MMP13 | |
| Hydrochloric Acid SCHEMBL2804437 | 0.66 | DPP7 (0.43) | DPP4DPP7DPP9DPP8FAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1461313-B1 | HUMAN ADAM-10 INHIBITORS | EXELIXIS INC (US) | 2009-08-05 | — | — | EP | disclosed |