Fluoride

Fluoride

SCHEMBL439611

CCCCCCCCCCCCCCCCCCC(N)(CC(O)(O)O)C(C)N.F.F

nearest known ligand 0.39

Full drug profile on Sugi Atlas →

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
FDPS P14324 10/20 0.39
SMPD1 P17405 4/20 0.39
SPHK1 Q9NYA1 1/20 0.37
GGPS1 O95749 5/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3794088 0.98 FDPS (0.40) FDPSSMPD1SPHK1GGPS1
SCHEMBL15573847 0.84 OPRM1 (0.42) FDPSSMPD1SPHK1GGPS1
SCHEMBL11792783 0.84 OPRM1 (0.42) FDPSSMPD1SPHK1GGPS1
SCHEMBL8071809 0.84 OPRM1 (0.42) FDPSSMPD1SPHK1GGPS1
SCHEMBL19253997 0.84 OPRM1 (0.42) FDPSSMPD1SPHK1GGPS1
Fluoride SCHEMBL5521472 0.76 FDPS (0.40) FDPSSMPD1SPHK1GGPS1
SCHEMBL9508445 0.75 OPRM1 (0.40) FDPSSMPD1SPHK1
SCHEMBL9494558 0.74 FAAH (0.44) SPHK1
SCHEMBL6558334 0.74 FDPS (0.45) FDPSSMPD1SPHK1GGPS1
SCHEMBL21903335 0.74 SPHK1 (0.43) FDPSSMPD1SPHK1GGPS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1001 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4392003-A1 PERSONAL CARE COMPOSITIONS Colgate-Palmolive Company (US) 2024-07-03 EP claimed
US-11998628-B2 Personal care compositions COLGATE-PALMOLIVE COMPANY (US) 2024-06-04 US claimed
WO-2023086227-A1 PERSONAL CARE COMPOSITIONS COLGATE-PALMOLIVE COMPANY (US) 2023-05-19 WO claimed
US-20230145870-A1 Personal Care Compositions COLGATE-PALMOLIVE COMPANY (US) 2023-05-11 US claimed
US-11484503-B2 Tablet comprising separate binder and erythritol FERTIN PHARMA A/S (DK) 2022-11-01 US claimed
WO-2021067216-A1 HAIR TREATMENT COMPOSITION L'OREAL (FR) 2021-04-08 WO claimed
US-20210093542-A1 HAIR TREATMENT COMPOSITION L'OREAL (FR) 2021-04-01 US claimed
WO-2017185147-A1 NANOSTRUCTURED LIPID CARRIERS AND METHODS FOR MAKING AND USING THEM L'OREAL (FR) 2017-11-02 WO claimed
WO-2017185155-A1 NANOSTRUCTURED LIPID CARRIERS AND METHODS FOR MAKING AND USING THEM L'OREAL (FR) 2017-11-02 WO claimed
US-20140234225-A1 METHOD OF TREATMENT USING NANOPARTICULATE COMPOSITIONS HAVING LYSOZYME AS A SURFACE STABILIZER ALKERMES PHARMA IRELAND LIMITED (IE) 2014-08-21 US claimed
US-20040258758-A1 Nanoparticulate topiramate formulations ELAN PHARMA INTERNATIONAL, LTD. 2004-12-23 US claimed
EP-1471887-A2 NANOPARTICULATE COMPOSITIONS HAVING LYSOZYME AS A SURFACE STABILIZER Elan Pharma International Limited (IE) 2004-11-03 EP claimed
US-20040208833-A1 Novel fluticasone formulations ELAN PHARMA INTERNATIONAL LTD. 2004-10-21 US claimed
WO-2004078162-A1 NANOPARTICULATE TOPIRAMATE FORMULATIONS ELAN PHARMA INTERNATIONAL LTD. (IE) 2004-09-16 WO claimed
US-20040164194-A1 System and method for milling materials ELAN PHARMA INTERNATIONAL LIMITED 2004-08-26 US claimed
WO-2004069225-A1 NOVEL FLUTICASONE FORMULATIONS ELAN PHARMA INTERNATIONAL LTD. (IE) 2004-08-19 WO claimed
WO-2004050059-A1 LOW VISCOSITY LIQUID DOSAGE FORMS ELAN PHARMA INTERNATIONAL LTD. (IE) 2004-06-17 WO claimed
US-20040105889-A1 Low viscosity liquid dosage forms ELAN PHARMA INTERNATIONAL LIMITED 2004-06-03 US claimed
US-20030185869-A1 Having lysozyme adsorbed onto or associated with the surface of an active agent ELAN PHARMA INTERNATIONAL LTD. 2003-10-02 US claimed
WO-2003066021-A2 DRUG NANOPARTICLES WITH LYSOZYME SURFACE STABILISER ELAN PHARMA INTERNATIONAL, LTD. (IE) 2003-08-14 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210093542-A1 HAIR TREATMENT COMPOSITION SORD, DPM1, HOGA1 FDPS 4728/4885SMPD1 372/4885SPHK1 231/4885
US-20040258758-A1 Nanoparticulate topiramate formulations FAH, MTHFD1, DHODH FDPS 229/4885SMPD1 1881/4885SPHK1 996/4885
US-20140234225-A1 METHOD OF TREATMENT USING NANOPARTICULATE COMPOSITIONS HAVING LYSOZYME AS A SURFACE STABILIZER LPO, LCT, LIPA FDPS 2908/4885SMPD1 75/4885SPHK1 1841/4885
US-20030185869-A1 Having lysozyme adsorbed onto or associated with the surface of an active agent LPO, LCT, CTSA FDPS 3804/4885SMPD1 80/4885SPHK1 2976/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.