Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 6/20 | 0.46 |
| ▸ | BCHE | P06276 | 5/20 | 0.46 |
| ▸ | GRIN1 | Q05586 | 5/20 | 0.46 |
| ▸ | GRIN2A | Q12879 | 5/20 | 0.46 |
| ▸ | HTR5A | P47898 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 3/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | TNF | P01375 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | METAP2 | P50579 | 1/20 | 0.36 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.36 |
| ▸ | AXL | P30530 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL438239 | 0.86 | ACHE (0.46) | ACHEBCHEGRIN1GRIN2AHTR5A | |
| SCHEMBL439464 | 0.81 | NR4A2 (0.55) | ACHEBCHEGRIN1GRIN2APARP1 | |
| SCHEMBL10385174 | 0.81 | BCHE (0.45) | ACHEBCHEGRIN1GRIN2APARP1 | |
| SCHEMBL439853 | 0.79 | BCHE (0.43) | ACHEBCHEGRIN1GRIN2APARP1 | |
| SCHEMBL442137 | 0.79 | HTT (0.49) | ACHEBCHEGRIN1GRIN2ALMNA | |
| SCHEMBL440082 | 0.79 | LMNA (0.47) | ACHEBCHEGRIN1GRIN2APARP1 | |
| SCHEMBL1035213 | 0.79 | PARP1 (0.41) | HTR5APARP1LMNATNF | |
| SCHEMBL439770 | 0.78 | BACE1 (0.42) | MAP4K4BACE1CYP1A2AXL | |
| SCHEMBL436602 | 0.75 | ACHE (0.44) | ACHENR4A2 | |
| SCHEMBL5747612 | 0.75 | LMNA (0.39) | HTR5APARP1LMNATNF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065166-A1 | Bone Modulators And Methods Therewith | ESPINA VIRGINIA (US) | 2012-03-15 | — | — | US | disclosed |