SCHEMBL44081

SCHEMBL44081

Cc1ccc(N(CCO)CCO)cc1C

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.53
KMT2A Q03164 4/20 0.53
RAB9A P51151 4/20 0.53
LMNA P02545 3/20 0.53
SMN1; SMN2 Q16637 3/20 0.53
NPC1 O15118 3/20 0.53
MEN1 O00255 2/20 0.53
TDP1 Q9NUW8 2/20 0.53
GAA P10253 1/20 0.53
PKM P14618 1/20 0.53
HTT P42858 1/20 0.53
MCL1 Q07820 1/20 0.53
POLB P06746 1/20 0.53
MAPK1 P28482 1/20 0.53
MMP14 P50281 1/20 0.53
L3MBTL1 Q9Y468 1/20 0.53
S1PR1 P21453 4/20 0.49
ALDH1A1 P00352 5/20 0.42
TP53 P04637 1/20 0.41
ATM Q13315 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10208385 0.93 MAPT (0.48) MAPTKMT2ARAB9ALMNASMN1; SMN2
SCHEMBL13412506 0.90 S1PR1 (0.56) MAPTKMT2ARAB9ALMNASMN1; SMN2
SCHEMBL11125633 0.88 ALDH1A1 (0.47) MAPTKMT2ARAB9ALMNASMN1; SMN2
SCHEMBL11173721 0.84 ALDH1A1 (0.55) MAPTKMT2ARAB9ALMNASMN1; SMN2
SCHEMBL10780791 0.84 MAPT (0.61) MAPTKMT2ARAB9ALMNASMN1; SMN2
SCHEMBL1598703 0.84 MAPT (0.47) MAPTKMT2ARAB9ALMNASMN1; SMN2
SCHEMBL10776359 0.84 MAPT (0.54) MAPTKMT2ARAB9ALMNASMN1; SMN2
SCHEMBL15477661 0.82 KMT2A (0.49) MAPTKMT2ARAB9ALMNASMN1; SMN2
SCHEMBL11158050 0.82 MAPT (0.60) MAPTKMT2ARAB9ALMNASMN1; SMN2
SCHEMBL10533867 0.82 MAPT (0.56) MAPTKMT2ARAB9ALMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 570 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008122596-A2 CURABLE THERAPEUTIC IMPLANT COMPOSITION CINVENTION AG (DE) 2008-10-16 WO claimed
US-20080248086-A1 CURABLE THERAPEUTIC IMPLANT COMPOSITION CINVENTION AG (DE) 2008-10-09 US claimed
US-20260144714-A1 KIT FOR PREPARING CURABLE COMPOSITION FOR DENTAL MATERIAL, CURABLE COMPOSITION FOR DENTAL MATERIAL, AND DENTAL MATERIAL MITSUI CHEMICALS, INC. (JP) 2026-05-28 US disclosed
US-12622847-B2 Organosilicon compound and dental composition containing same KURARAY NORITAKE DENTAL INC. (JP) 2026-05-12 US disclosed
US-20260124121-A1 POLYMERIZABLE DENTAL COMPOSITION TROETSCHLER TOBIAS (DE) 2026-05-07 US disclosed
EP-3861977-B1 (METH)ACRYLATE, MONOMER COMPOSITION, MOLDED BODY, COMPOSITION FOR DENTAL MATERIAL, AND DENTAL MATERIAL MITSUI CHEMICALS INC (JP) 2026-05-06 EP disclosed
EP-4736833-A1 POLYMERIZABLE DENTAL COMPOSITION DENTSPLY SIRONA Inc. (US) 2026-05-06 EP disclosed
EP-4725470-A1 CURABLE DENTAL COMPOSITION Kuraray Noritake Dental Inc. (JP) 2026-04-15 EP disclosed
US-12564543-B2 Dental composition KURARAY NORITAKE DENTAL INC. (JP) 2026-03-03 US disclosed
US-12527725-B2 Solvent-free dental adhesive composition KURARAY NORITAKE DENTAL INC. (JP) 2026-01-20 US disclosed
US-12478562-B2 Dental restoration material composition KURARAY NORITAKE DENTAL INC. (JP) 2025-11-25 US disclosed
US-4327014-A INORGANIC NITRIDE FILLERS IN BINDERS OF PENTAERYTHRITOL TRI-OR TETRA-ACRYLATES KANEBO LTD. (JP) 1982-04-27 US disclosed
US-4308014-A AN UNSATURATED ESTER OR AMIDE, A TITANIUM ALKOXIDE OR A TRIALKOXY SILANE, A FREE RADICAL CATALYST AND AN ACTIVATOR; DENTISTRY KANEBO LTD. (JP) 1981-12-29 US disclosed
US-4261879-A DENTISTRY JOHNSON & JOHNSON DENTAL PRODUCTS COMPANY (US) 1981-04-14 US disclosed
EP-0017937-A2 Bonding compositions to the hard tissue of human body KANEBO, LTD. (JP) 1980-10-29 EP disclosed
EP-0017936-A2 Compositions of restorative material especially suitable for dental filling material KANEBO, LTD. (JP) 1980-10-29 EP disclosed
EP-0017151-A2 Cold curing materials for dental purposes with polymerisation-active sulfones BAYER AG (DE) 1980-10-15 EP disclosed
US-4156766-A ACRYLATES AND/OR METHACRYLATES, P-T-BUTYLBENZOYL PEROXIDE, AMINE ACCELERATOR; DENTAL RESTORATIVE MATERIAL, HEAT RESISTANT JOHNSON & JOHNSON (US) 1979-05-29 US disclosed
US-4010545-A Adhesive bonding to teeth of orthodontic brackets and the like JOHNSON & JOHNSON (US) 1977-03-08 US disclosed
US-3941580-A N,N-BIS(2-METHOXY-3,6-DICHLORO-BENZOYL-OXYALKYL) ANILINES VELSICOL CHEMICAL CORPORATION (US) 1976-03-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12527725-B2 Solvent-free dental adhesive composition CDH1, ITGA1, ITGB8 MAPT 1040/4885KMT2A 2358/4885RAB9A 1701/4885
US-20260144714-A1 KIT FOR PREPARING CURABLE COMPOSITION FOR DENTAL MATERIAL, CURABLE COMPOSITION FOR DENTAL MATERIAL, AND DENTAL MATERIAL CAD, KIT, ILK MAPT 3535/4885KMT2A 270/4885RAB9A 2393/4885
US-12564543-B2 Dental composition CAD, ARCN1, MAT1A MAPT 344/4885KMT2A 1041/4885RAB9A 2847/4885
US-12478562-B2 Dental restoration material composition CAD, MAT2B, RER1 MAPT 2163/4885KMT2A 643/4885RAB9A 2122/4885
US-12622847-B2 Organosilicon compound and dental composition containing same MSL1, ITGA1, ITGAL MAPT 4304/4885KMT2A 2306/4885RAB9A 3519/4885
US-20260124121-A1 POLYMERIZABLE DENTAL COMPOSITION F12, RAD51, PFN1 MAPT 999/4885KMT2A 3311/4885RAB9A 1440/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.