Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.34 |
| ▸ | TERT | O14746 | 1/20 | 0.34 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 3/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
| ▸ | CCR5 | P51681 | 1/20 | 0.33 |
| ▸ | HRH2 | P25021 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4403746 | 0.94 | CHRM2 (0.36) | SRD5A2MEN1KMT2ACHRM2CHRM1 | |
| SCHEMBL4405956 | 0.90 | FAAH (0.34) | SRD5A2MEN1KMT2ACHRM2CHRM1 | |
| SCHEMBL4411341 | 0.90 | HTR1A (0.34) | SRD5A2MEN1KMT2APDE3BPDE3A | |
| SCHEMBL914670 | 0.87 | SRD5A2 (0.43) | SRD5A2MEN1KMT2ATMEM97ADRA2A | |
| SCHEMBL4406699 | 0.84 | KMT2A (0.34) | SRD5A2MEN1KMT2ACHRM2CHRM1 | |
| SCHEMBL4396316 | 0.84 | KMT2A (0.34) | SRD5A2MEN1KMT2ACHRM2CHRM1 | |
| SCHEMBL4400766 | 0.84 | TERT (0.37) | TERTHTR2AFAAHADRA2AADRA2B | |
| SCHEMBL4405632 | 0.84 | MAOB (0.38) | HTR2AMAOAMAOBADRA2AADRA2B | |
| SCHEMBL4411388 | 0.84 | CHRM2 (0.34) | SRD5A2MEN1KMT2ACHRM2CHRM1 | |
| SCHEMBL4396602 | 0.83 | SRD5A2 (0.47) | SRD5A2MEN1KMT2ATMEM97FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1720859-B1 | CHEMOKINE RECEPTOR ANTAGONISTS | NOVARTIS AG (CH) | 2009-12-23 | — | — | EP | claimed |