Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRN | P28799 | 1/20 | 0.63 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.63 |
| ▸ | HPGD | P15428 | 3/20 | 0.63 |
| ▸ | MEN1 | O00255 | 3/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | TAS1R3 | Q7RTX0 | 4/20 | 0.51 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.51 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13754407 | 0.86 | GRN (0.60) | GRNSORT1HPGDMEN1KMT2A | |
| SCHEMBL27405373 | 0.86 | TAS1R3 (0.55) | GRNSORT1HPGDMEN1KMT2A | |
| SCHEMBL4753159 | 0.84 | CA2 (0.68) | GRNSORT1HPGDMEN1KMT2A | |
| SCHEMBL4753157 | 0.84 | CA2 (0.68) | GRNSORT1HPGDMEN1KMT2A | |
| SCHEMBL16987307 | 0.84 | MAPT (0.53) | GRNSORT1HPGDMEN1KMT2A | |
| SCHEMBL531992 | 0.84 | SMN1; SMN2 (0.57) | GRNSORT1MEN1KMT2AMAPT | |
| SCHEMBL8185308 | 0.84 | CA2 (0.68) | GRNSORT1HPGDMEN1KMT2A | |
| SCHEMBL20791763 | 0.83 | TAS1R3 (0.47) | GRNSORT1HPGDMEN1KMT2A | |
| SCHEMBL13544725 | 0.83 | GRN (0.47) | GRNSORT1HPGDMEN1KMT2A | |
| SCHEMBL14627779 | 0.83 | GRN (0.61) | GRNSORT1HPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6362369-B1 | — | — | None | — | — | US | disclosed |
| US-20240208968-A1 | ALPHA V BETA 6 AND ALPHA V BETA 1 INTEGRIN INHIBITORS AND USES THEREOF | DICE MOLECULES SV, INC. | 2024-06-27 | — | — | US | disclosed |
| WO-2024102989-A1 | NON-PEPTIDIC SARS-COV-2 MAIN PROTEASE INHIBITORS | THE TEXAS A&M UNIVERSITY SYSTEM (US) | 2024-05-16 | — | — | WO | disclosed |
| US-11028090-B2 | [1,2,4]Triazolo[4,3-a]quinoxaline derivative, method for preparing same, and pharmaceutical composition for preventing or treating BET protein-related diseases, containing same as active ingredient | DONG WHA PHARM. CO., LTD. (KR) | 2021-06-08 | — | — | US | disclosed |
| US-20200039984-A1 | Novel [1,2,4]Triazolo[4,3-a]Quinoxaline Derivative, Method For Preparing Same, And Pharmaceutical Composition For Preventing Or Treating BET Protein-Related Diseases, Containing Same As Active Ingredient | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2020-02-06 | — | — | US | disclosed |
| US-20100234378-A1 | ALKYLSULFONAMIDE-SUBSTITUTED TRIAZOLES AS MATRIX METALLOPROTEASE INHIBITORS | ARRAY BIOPHARMA INC. (US) | 2010-09-16 | — | — | US | disclosed |
| US-20100234378-A1 | ALKYLSULFONAMIDE-SUBSTITUTED TRIAZOLES AS MATRIX METALLOPROTEASE INHIBITORS | ARRAY BIOPHARMA INC. (US) | 2010-09-16 | — | — | US | disclosed |
| US-7576117-B1 | Cyclic amine CCR3 antagonist | TEIJIN LIMITED (JP) | 2009-08-18 | — | — | US | disclosed |
| US-7576117-B1 | Cyclic amine CCR3 antagonist | TEIJIN LIMITED (JP) | 2009-08-18 | — | — | US | disclosed |
| EP-1700844-B1 | Phthalic acid diamide derivatives, agricultural and horticultural insecticides and a method for application of the insecticides | NIHON NOHYAKU CO LTD (JP) | 2009-01-14 | — | — | EP | disclosed |
| US-20070010509-A1 | Cycloamine ccr5 receptor antagonists | TEIJIN PHARMA LIMITED (JP) | 2007-01-11 | — | — | US | disclosed |
| EP-1700844-A1 | Phthalic acid diamide derivatives, agricultural and horticultural insecticides and a method for application of the insecticides | Nihon Nohyaku Co., Ltd. (JP) | 2006-09-13 | — | — | EP | disclosed |
| EP-0919542-B1 | Phthalic acid diamide derivatives, agricultural and horticultural insecticides, and a method for application of the insecticides | NIHON NOHYAKU CO LTD (JP) | 2006-08-23 | — | — | EP | disclosed |
| EP-1447396-A1 | Phthalic acid diamide derivatives, agriculture and horticultural insecticides, and a method for application of the insecticides | NIHON NOHYAKU CO., LTD. (JP) | 2004-08-18 | — | — | EP | disclosed |
| US-6559341-B2 | Phthalic acid diamide derivatives, fluorine-containing aniline compounds as starting material, agricultural and horticultural insecticides, and a method for application of the insecticides | NIHON NOHYAKU CO., LTD. (JP) | 2003-05-06 | — | — | US | disclosed |
| US-20030055287-A1 | Phthalic acid diamide derivatives, fluorine-containing aniline compounds as starting material, agricultural and horticultural insecticides, and a method for application of the insecticides | AIR MOTION TECHNOLOGIES, LLC | 2003-03-20 | — | — | US | disclosed |
| US-6362369-B2 | CONTROLLING INSECTS IN CROPS | NIHON NOHYAKU CO., LTD. (JP) | 2002-03-26 | — | — | US | disclosed |
| US-20010041814-A1 | PHTHALIC ACID DIAMIDE DERIVATIVES FLUORINE-CONTAINING ANILINE COMPOUNDS AS STARTING MATERIAL, AGRICULTURAL AND HORTICULTURAL INSECTICIDES, AND A METHOD FOR APPLICATION OF THE INSECTICIDES | NIHON NOHYAKU CO., LTD. (JP) | 2001-11-15 | — | — | US | disclosed |
| EP-0919542-A2 | Phthalic acid diamide derivatives, agricultural and horticultural insecticides, and a method for application of the insecticides | NIHON NOHYAKU CO., LTD. (JP) | 1999-06-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240208968-A1 | ALPHA V BETA 6 AND ALPHA V BETA 1 INTEGRIN INHIBITORS AND USES THEREOF | ITGB1, ITGA1, ITGAV | GRN 4112/4885SORT1 1482/4885HPGD 2690/4885 |
| US-20100234378-A1 | ALKYLSULFONAMIDE-SUBSTITUTED TRIAZOLES AS MATRIX METALLOPROTEASE INHIBITORS | MMP3, MMP11, MMP13 | GRN 4137/4885SORT1 3796/4885HPGD 788/4885 |
| US-11028090-B2 | [1,2,4]Triazolo[4,3-a]quinoxaline derivative, method for preparing same, and pharmaceutical composition for preventing or treating BET protein-related diseases, containing same as active ingredient | BRD4, BET1, BRD3 | GRN 2787/4885SORT1 4865/4885HPGD 2639/4885 |
| US-20200039984-A1 | Novel [1,2,4]Triazolo[4,3-a]Quinoxaline Derivative, Method For Preparing Same, And Pharmaceutical Composition For Preventing Or Treating BET Protein-Related Diseases, Containing Same As Active Ingredient | BRD4, BET1, BRD3 | GRN 2823/4885SORT1 4860/4885HPGD 2952/4885 |
| US-20010041814-A1 | PHTHALIC ACID DIAMIDE DERIVATIVES FLUORINE-CONTAINING ANILINE COMPOUNDS AS STARTING MATERIAL, AGRICULTURAL AND HORTICULTURAL INSECTICIDES, AND A METHOD FOR APPLICATION OF THE INSECTICIDES | DDT, AFF1, BCL2L2 | GRN 4318/4885SORT1 2099/4885HPGD 3918/4885 |
| US-20070010509-A1 | Cycloamine ccr5 receptor antagonists | CCR5, CCR2, CCR1 | GRN 2167/4885SORT1 4408/4885HPGD 1186/4885 |
| US-20030055287-A1 | Phthalic acid diamide derivatives, fluorine-containing aniline compounds as starting material, agricultural and horticultural insecticides, and a method for application of the insecticides | DDT, BCL2A1, BCL2L2 | GRN 4386/4885SORT1 2059/4885HPGD 3799/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.