Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 1/20 | 0.37 |
| ▸ | CCR5 | P51681 | 1/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5029431 | 0.89 | CCR2 (0.37) | CCR2CCR5PIK3CDPIK3R1PIK3CA | |
| SCHEMBL4417546 | 0.84 | CCR2 (0.32) | CCR2CCR5 | |
| SCHEMBL4424140 | 0.82 | IRAK4 (0.41) | CCR2 | |
| SCHEMBL4426067 | 0.81 | CNR1 (0.40) | CCR2CCR5 | |
| SCHEMBL4551359 | 0.81 | NSD2 (0.47) | — | |
| SCHEMBL4417401 | 0.81 | IRAK4 (0.39) | CCR2CCR5 | |
| SCHEMBL4418746 | 0.81 | CCR2 (0.49) | CCR2CCR5 | |
| SCHEMBL4427802 | 0.81 | F10 (0.34) | CCR2CCR5 | |
| SCHEMBL4417824 | 0.80 | FFAR2 (0.33) | CCR2CCR5 | |
| SCHEMBL4419993 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1606255-B1 | CYCLIC DERIVATIVES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | BRISTOL MYERS SQUIBB CO (US) | 2009-11-11 | — | — | EP | claimed |