Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.34 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.34 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.34 |
| ▸ | KMO | O15229 | 2/20 | 0.34 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SPR | P35270 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29696120 | 1.00 | NPC1 (0.39) | NPC1RAB9ATLR7MEN1KMT2A | |
| SCHEMBL447507 | 0.88 | NPC1 (0.38) | NPC1RAB9ATLR7MEN1KMT2A | |
| SCHEMBL16152204 | 0.86 | MEN1 (0.40) | NPC1RAB9AMEN1KMT2AKDM4E | |
| SCHEMBL1138695 | 0.84 | NPC1 (0.37) | NPC1RAB9ATLR7MEN1KMT2A | |
| SCHEMBL444100 | 0.81 | TLR7 (0.42) | NPC1RAB9ATLR7MEN1KMT2A | |
| SCHEMBL12270857 | 0.80 | NPC1 (0.53) | NPC1RAB9AKMT2AKDM4EGRM4 | |
| SCHEMBL447506 | 0.77 | KDM4E (0.42) | NPC1RAB9AMEN1KMT2AKDM4E | |
| SCHEMBL25247534 | 0.76 | TLR7 (0.38) | NPC1RAB9ATLR7KMT2AEGLN2 | |
| SCHEMBL1138578 | 0.76 | PDK1 (0.35) | NPC1RAB9ATLR7MEN1KMT2A | |
| SCHEMBL1138693 | 0.74 | MEN1 (0.39) | NPC1RAB9AMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2437854-B1 | COMPOSITIONS COMPRISING BORINIC ESTERS | COLGATE PALMOLIVE CO (US) | 2018-08-08 | — | — | EP | claimed |
| US-8852559-B2 | Borinic compositions | COLGATE-PALMOLIVE COMPANY (US) | 2014-10-07 | — | — | US | claimed |
| US-20120064017-A1 | BORINIC COMPOSITIONS | COLGATE-PALMOLIVE COMPANY (US) | 2012-03-15 | — | — | US | claimed |
| US-20120052025-A1 | BORINIC COMPOSITIONS | COLGATE-PALMOLIVE COMPANY (US) | 2012-03-01 | — | — | US | claimed |
| EP-1765358-B1 | TREATMENT OR PREVENTION OF SKIN CONDITIONS OR TISSUE CONDITIONS IN ANIMALS USING BORYLOXYPYRIDYLMETHANONES | ANACOR PHARMACEUTICALS INC (US) | 2011-02-23 | — | — | EP | claimed |
| US-7652000-B2 | Boron-containing compounds and methods of use | ANACOR PHARMACEUTICALS, INC. (US) | 2010-01-26 | — | — | US | claimed |
| EP-1765360-B1 | ANTI-VIRAL USES OF BORINIC ACID COMPLEXES | ANACOR PHARMACEUTICALS INC (US) | 2009-11-11 | — | — | EP | claimed |
| WO-2009045397-A1 | METHODS FOR TREATING POLYCYSTIC KIDNEY DESEASE (PKD) OR OTHER CYST FORMING DISEASES | STOWERS INSTITUTE FOR MEDICAL RESEARCH (US) | 2009-04-09 | — | — | WO | claimed |
| US-20080269123-A1 | Methods for treating polycystic kidney disease (PKD) or other cyst forming diseases | STOWERS MEDICAL INSTITUTE INC. | 2008-10-30 | — | — | US | claimed |
| EP-1965647-A2 | PROCESS FOR MANUFACTURING PICOLINATE BORINIC ESTERS | Anacor Pharmaceuticals, Inc. (US) | 2008-09-10 | — | — | EP | claimed |
| EP-1765360-A2 | ANTI-VIRAL USES OF BORINIC ACID COMPLEXES | Anacor Pharmaceuticals, Inc. (US) | 2007-03-28 | — | — | EP | claimed |
| EP-1765358-A2 | TREATMENT OR PREVENTION OF SKIN CONDITIONS OR TISSUE CONDITIONS IN ANIMALS USING BORYLOXYPYRIDYLMETHANONES | Anacor Pharmaceuticals, Inc. (US) | 2007-03-28 | — | — | EP | claimed |
| US-20060217347-A1 | Topical formulations of borinic acid antibiotics and their methods of use | ANACOR PHARMACEUTICALS, INC. | 2006-09-28 | — | — | US | claimed |
| WO-2006102604-A2 | TOPICAL FORMULATIONS OF BORINIC ACID ANTIBODIES AND THEIR METHODS OF USE | ANACOR PHARMACEUTICALS, INC. (US) | 2006-09-28 | — | — | WO | claimed |
| WO-2006085932-A2 | ANTI-VIRAL USES OF BORINIC ACID COMPLEXES | ANACOR PHARMACEUTICALS, INC. (US) | 2006-08-17 | — | — | WO | claimed |
| US-20060019927-A1 | Anti-viral uses of borinic acid complexes | ANACOR PHARMACEUTICALS, INC. | 2006-01-26 | — | — | US | claimed |
| US-20060014723-A1 | Anti-parasitic uses of borinic acid complexes | ANACOR PHARMACEUTICALS, INC. | 2006-01-19 | — | — | US | claimed |
| US-20060009422-A1 | Boron-containing compounds and methods of use | ANACOR PHARMACEUTICALS, INC. | 2006-01-12 | — | — | US | claimed |
| WO-2005123094-A2 | TREATMENT OR PREVENTION OF SKIN CONDITIONS OR TISSUE CONDITIONS IN ANIMALS USING BORYLOXYPYRIDYLMETHANONES | ANACOR PHARMACEUTICALS, INC. (US) | 2005-12-29 | — | — | WO | claimed |
| WO-2005123095-A1 | ANTI-PARASITIC USES OF BORINIC ACID COMPLEXES | ANACOR PHARMACEUTICALS, INC. (US) | 2005-12-29 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060217347-A1 | Topical formulations of borinic acid antibiotics and their methods of use | CUTA, BROX, BTD | NPC1 494/4885RAB9A 2449/4885TLR7 161/4885 |
| US-20060014723-A1 | Anti-parasitic uses of borinic acid complexes | BPGM, HRH1, HRH3 | NPC1 1480/4885RAB9A 2635/4885TLR7 1610/4885 |
| US-20120064017-A1 | BORINIC COMPOSITIONS | BACH1, FHIT, BPNT1 | NPC1 2356/4885RAB9A 2104/4885TLR7 1475/4885 |
| US-20060009422-A1 | Boron-containing compounds and methods of use | BROX, BTD, PBDC1 | NPC1 143/4885RAB9A 2857/4885TLR7 80/4885 |
| US-20120052025-A1 | BORINIC COMPOSITIONS | CCL11, BDKRB2, BTD | NPC1 792/4885RAB9A 2053/4885TLR7 516/4885 |
| US-20060019927-A1 | Anti-viral uses of borinic acid complexes | SSB, BPGM, HAVCR2 | NPC1 1724/4885RAB9A 3638/4885TLR7 440/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.