Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCEH1 | Q6PIU2 | 2/20 | 0.43 |
| ▸ | HTR1A | P08908 | 2/20 | 0.41 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HTR3A | P46098 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 2/20 | 0.38 |
| ▸ | HTR2C | P28335 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4426602 | 0.90 | PLA2G2A (0.42) | MGLLALDH1A1HSD17B10 | |
| SCHEMBL3919666 | 0.86 | HTR2A (0.51) | KCNA3ALDH1A1HPGDHTR2AHTR2C | |
| SCHEMBL4417423 | 0.86 | MGLL (0.43) | MGLLALDH1A1HTR2AHTR2CSLC6A4 | |
| SCHEMBL4417700 | 0.85 | NCEH1 (0.42) | NCEH1HTR1AALDH1A1HSD17B10HTR2A | |
| SCHEMBL4425475 | 0.85 | MGLL (0.38) | NCEH1HTR1AMGLLALDH1A1HSD17B10 | |
| SCHEMBL4423636 | 0.85 | ALDH1A1 (0.47) | MGLLALDH1A1HPGDHTR2AHTR2C | |
| SCHEMBL4429632 | 0.84 | ALDH1A1 (0.43) | ALDH1A1HSD17B10HTR2AHTR2CSLC6A4 | |
| SCHEMBL4552635 | 0.84 | CNR1 (0.40) | NCEH1HTR1AKCNA3DRD2ADRA1A | |
| SCHEMBL4417093 | 0.84 | MAPT (0.43) | NCEH1MGLLALDH1A1HSD17B10HTR2A | |
| SCHEMBL4423695 | 0.83 | HTR2A (0.41) | NCEH1MGLLALDH1A1HSD17B10HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1583742-B1 | CB 1 RECEPTOUR INVERSE AGONISTS | HOFFMANN LA ROCHE (CH) | 2009-12-02 | — | — | EP | claimed |