Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CRHBP | P24387 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.42 |
| ▸ | MGLL | Q99685 | 3/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 3/20 | 0.40 |
| ▸ | HTR2C | P28335 | 3/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4423695 | 0.92 | HTR2A (0.41) | ALDH1A1MAPTKMT2AMEN1LMNA | |
| SCHEMBL4429632 | 0.90 | ALDH1A1 (0.43) | ALDH1A1PLA2G2AHTR2AHTR2CSLC6A4 | |
| SCHEMBL4417423 | 0.90 | MGLL (0.43) | ALDH1A1MAPTKMT2AMEN1LMNA | |
| SCHEMBL4418725 | 0.90 | HTR2A (0.46) | HTR2AHTR2CSLC6A4CNR2 | |
| SCHEMBL4417093 | 0.90 | MAPT (0.43) | ALDH1A1MAPTMGLLACHEHTR2A | |
| SCHEMBL4419276 | 0.90 | ACHE (0.39) | ALDH1A1MAPTKMT2AMEN1LMNA | |
| SCHEMBL4426602 | 0.89 | PLA2G2A (0.42) | ALDH1A1TDP1PLA2G2AMGLLACHE | |
| SCHEMBL4425227 | 0.88 | CNR1 (0.41) | ALDH1A1MGLLACHEHTR2AHTR2C | |
| SCHEMBL4422250 | 0.88 | HTR2A (0.46) | ALDH1A1MAPTKMT2AMEN1HPGD | |
| SCHEMBL5048696 | 0.87 | CDC25A (0.43) | ALDH1A1MAPTKMT2AMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1583742-B1 | CB 1 RECEPTOUR INVERSE AGONISTS | HOFFMANN LA ROCHE (CH) | 2009-12-02 | — | — | EP | claimed |