SCHEMBL4426720

SCHEMBL4426720

NCCCCCC(=O)OC(=O)O.O=C1C=CC(=O)N1CC1(N2C(=O)CCC2=O)CCCCC1

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 4/20 0.33
PTGS2 P35354 4/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6260834 0.78 MGLL (0.32)
SCHEMBL725035 0.75
SCHEMBL1766181 0.75 PTGS1 (0.36) PTGS1PTGS2
Cyclohexane SCHEMBL3760865 0.72 LMNA (0.50)
SCHEMBL45794 0.71 PTGS1 (0.33) PTGS1PTGS2
SCHEMBL1682194 0.68 LMNA (0.56)
SCHEMBL1019147 0.66
SCHEMBL28668492 0.66 PTGS1 (0.56) PTGS1PTGS2
SCHEMBL9841169 0.65 PTGS1 (0.37) PTGS1PTGS2
SCHEMBL28600387 0.64 ALDH1A1 (0.38) PTGS1PTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11185594-B2 (Anti-HER2 antibody)-drug conjugate DAIICHI SANKYO COMPANY, LIMITED (JP) 2021-11-30 US disclosed
EP-3130608-B1 (ANTI-HER2 ANTIBODY)-DRUG CONJUGATE DAIICHI SANKYO CO LTD (JP) 2019-09-04 EP disclosed
EP-3130608-A1 (ANTI-HER2 ANTIBODY)-DRUG CONJUGATE Daiichi Sankyo Co., Ltd. (JP) 2017-02-15 EP disclosed
US-20170035906-A1 (ANTI-HER2 ANTIBODY)-DRUG CONJUGATE DAIICHI SANKYO COMPANY, LIMITED (JP) 2017-02-09 US disclosed
US-8323645-B2 Antibodies that bind OV064 and methods of use therefor MILLENNIUM PHARMACEUTICALS, INC. (US) 2012-12-04 US disclosed
US-20090208489-A1 Antibodies That Bind OV064 and Methods of Use Therefor MILLENNIUM PHARMACEUTICALS, INC. INTELLECTUAL PROPERTY GROUP (US) 2009-08-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170035906-A1 (ANTI-HER2 ANTIBODY)-DRUG CONJUGATE ERBB2, EGFR, LANCL2 PTGS1 2252/4885PTGS2 1946/4885
US-11185594-B2 (Anti-HER2 antibody)-drug conjugate ERBB2, EGFR, LANCL2 PTGS1 2252/4885PTGS2 1946/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.