Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | SLC6A9 | P48067 | 5/20 | 0.32 |
| ▸ | GRM5 | P41594 | 2/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3805129 | 0.83 | HTR2C (0.45) | HDAC1HDAC8HDAC6TP53MAPT | |
| SCHEMBL4432516 | 0.80 | HTR6 (0.37) | HDAC1HDAC8HDAC6 | |
| SCHEMBL3701560 | 0.77 | THRB (0.46) | TP53MAPT | |
| SCHEMBL16333316 | 0.74 | KMT2A (0.36) | MAPTSLC6A9 | |
| SCHEMBL3703976 | 0.73 | NOTUM (0.33) | SLC6A9GRM5 | |
| SCHEMBL4130894 | 0.73 | SLC6A9 (0.36) | TP53MAPTSLC6A9CA2CA4 | |
| SCHEMBL3707175 | 0.73 | SLC6A9 (0.33) | HDAC1HDAC8HDAC6TP53MAPT | |
| SCHEMBL3805131 | 0.72 | SLC6A9 (0.36) | TP53MAPTSLC6A9GRM5 | |
| SCHEMBL3697121 | 0.71 | NOTUM (0.34) | — | |
| SCHEMBL4130901 | 0.71 | TP53 (0.34) | TP53MAPTSLC6A9CA2CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2190822-B1 | 5-MEMBERED HETEROCYCLIC COMPOUNDS AS PROTON PUMP INHIBITORS | TAKEDA PHARMACEUTICAL (JP) | 2014-12-31 | — | — | EP | disclosed |
| US-20090156642-A1 | 5-Membered heterocyclic compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090156642-A1 | 5-Membered heterocyclic compound | CEL, PGA5, COG5 | HDAC1 466/4885HDAC8 696/4885HDAC6 63/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.