Sugi Predict

Sugi Predict / Compounds / SCHEMBL4439294

SCHEMBL4439294

SCHEMBL4439294

Cc1cc(C)cc(C2=NCCc3ccc(C)cc32)c1

nearest known ligand 0.48

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ MAPK10 P53779 12/20 0.48
▸ ALDH1A1 P00352 1/20 0.42
▸ LMNA P02545 1/20 0.42
▸ PARP1 P09874 1/20 0.39
▸ PARP10 Q53GL7 1/20 0.39
▸ MAPK14 Q16539 3/20 0.39
▸ MAPK9 P45984 2/20 0.39
▸ MAPK8 P45983 1/20 0.39
▸ CYP19A1 P11511 2/20 0.38
▸ CYP11B2 P19099 2/20 0.38
▸ CA1 P00915 1/20 0.37
▸ CA2 P00918 1/20 0.37
▸ CA7 P43166 1/20 0.37
▸ CA9 Q16790 1/20 0.37
▸ CA14 Q9ULX7 1/20 0.37
▸ PLG P00747 1/20 0.36
▸ PLAU P00749 1/20 0.36
▸ PLAT P00750 1/20 0.36
▸ KLK1 P06870 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28531265 0.85 MAPK10 (0.55) MAPK10ALDH1A1LMNAMAPK14MAPK9
SCHEMBL13389226 0.83 MAPK10 (0.41) MAPK10ALDH1A1LMNAMAPK14MAPK9
SCHEMBL1009906 0.77 MAOA (0.53) ALDH1A1PARP1PARP10CYP19A1CYP11B2
SCHEMBL29010811 0.76 MAPK10 (0.37) MAPK10ALDH1A1LMNAPARP1PARP10
SCHEMBL29498354 0.74 MAPK10 (0.62) MAPK10MAPK14MAPK9MAPK8
SCHEMBL28341380 0.74 MAPK10 (0.62) MAPK10MAPK14MAPK9MAPK8
SCHEMBL7702917 0.74 NPY5R (0.51) MAPK10ALDH1A1LMNAPARP1PARP10
SCHEMBL4439370 0.72 MAPK10 (0.58) MAPK10ALDH1A1LMNAMAPK14MAPK9
SCHEMBL13805616 0.71 NOS3 (0.49) MAPK10ALDH1A1LMNAMAPK14MAPK9
SCHEMBL11743377 0.70 PARP1 (0.39) MAPK10ALDH1A1PARP1PARP10CYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11495755-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2022-11-08 — — US disclosed
EP-3719099-B1 PHOSPHORESCENT MATERIALS UNIVERSAL DISPLAY CORP (US) 2022-09-14 — — EP disclosed
EP-3719099-A1 PHOSPHORESCENT MATERIALS Universal Display Corporation (US) 2020-10-07 — — EP disclosed
US-20200176693-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2020-06-04 — — US disclosed
US-20200176693-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2020-06-04 — — US disclosed
EP-3327100-B1 PHOSPHORESCENT MATERIALS UNIVERSAL DISPLAY CORP (US) 2020-05-06 — — EP disclosed
EP-3327100-B1 PHOSPHORESCENT MATERIALS UNIVERSAL DISPLAY CORP (US) 2020-05-06 — — EP disclosed
US-10600975-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2020-03-24 — — US disclosed
US-10600975-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2020-03-24 — — US disclosed
US-20190157576-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2019-05-23 — — US disclosed
EP-2489716-A2 Phosphorescent materials Universal Display Corporation (US) 2012-08-22 — — EP disclosed
EP-2489716-A2 Phosphorescent materials Universal Display Corporation (US) 2012-08-22 — — EP disclosed
EP-2465912-A1 Phosphorescent Materials Universal Display Corporation (US) 2012-06-20 — — EP disclosed
EP-2465912-A1 Phosphorescent Materials Universal Display Corporation (US) 2012-06-20 — — EP disclosed
EP-2121871-A2 PHOSPHORESCENT MATERIALS University Display Corporation (US) 2009-11-25 — — EP disclosed
US-20080261076-A1 Substituted 2-Phenyl quinoline complex with Iridium; high device efficiency, stability, and processibility UNIVERSAL DISPLAY CORPORATION (US) 2008-10-23 — — US disclosed
US-20080261076-A1 Substituted 2-Phenyl quinoline complex with Iridium; high device efficiency, stability, and processibility UNIVERSAL DISPLAY CORPORATION (US) 2008-10-23 — — US disclosed
US-20080261076-A1 Substituted 2-Phenyl quinoline complex with Iridium; high device efficiency, stability, and processibility UNIVERSAL DISPLAY CORPORATION (US) 2008-10-23 — — US disclosed
WO-2008109824-A2 PHOSPHORESCENT MATERIALS UNIVERSAL DISPLAY CORPORATION (US) 2008-09-12 — — WO disclosed
WO-2008109824-A2 PHOSPHORESCENT MATERIALS UNIVERSAL DISPLAY CORPORATION (US) 2008-09-12 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080261076-A1 Substituted 2-Phenyl quinoline complex with Iridium; high device efficiency, stability, and processibility PCID2, ICMT, ORAI2 MAPK10 3357/4885ALDH1A1 3830/4885LMNA 4175/4885
US-20200176693-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES RUVBL2, TERT, OR10J3 MAPK10 2448/4885ALDH1A1 1888/4885LMNA 3740/4885
US-11495755-B2 Organic electroluminescent materials and devices RUVBL2, TERT, OR10J3 MAPK10 2448/4885ALDH1A1 1888/4885LMNA 3740/4885
US-10600975-B2 Organic electroluminescent materials and devices TERT, OR10J3, RUVBL2 MAPK10 1554/4885ALDH1A1 1294/4885LMNA 4127/4885
US-20190157576-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES PIEZO1, ORAI2, PORCN MAPK10 2269/4885ALDH1A1 3140/4885LMNA 1976/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.